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门静脉肝神经鞘瘤病例报告:多模态影像表现

Case report of portal hepatic schwannoma: presentation of multimodality images.

作者信息

Amano Maki, Amano Yasuo, Takagi Ryo, Tang Xiaoyan, Omori Yuko, Okada Masahiro

机构信息

Department of Radiology, Nihon University Hospital, 1-6 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-8309, Japan.

Department of Pathology, Nihon University Hospital, Tokyo, 101-8309, Japan.

出版信息

BMC Gastroenterol. 2021 Apr 20;21(1):183. doi: 10.1186/s12876-021-01767-9.

Abstract

BACKGROUND

Portal hepatic schwannoma is a rare benign tumor and difficult to diagnose preoperatively because of its rarity and imaging manifestations that mimic malignancy. We present a case of portal hepatic schwannoma that showed moderate contrast enhancement on computed tomography (CT), extension along the bile duct on T2-weighted imaging and magnetic resonance cholangiopancreatography (MRCP), and uptake of F-fluorodeoxyglucose (FDG) on positron emission tomography.

CASE PRESENTATION

Ultrasonography at an annual health checkup identified a hepatic mass in a 38-year-old woman. CT showed a well-defined portal hepatic tumor with mild contrast enhancement. T2-weighted imaging and MRCP showed a clavate tumor extending along the intrahepatic bile ducts but no dilatation of the ducts. The tumor exhibited increased FDG uptake, such as maximum standardized uptake values of 5.0 and 6.5 in the early and late phases, respectively. Neither dilatation of intrahepatic bile ducts nor lymphadenopathy was identified, and the multimodality imaging suggested hepatic portal lymphoma, gastrointestinal tumor, or IgG4-related disease rather than cholangiocarcinoma. A needle biopsy via endoscopic ultrasonography was performed, and immunohistology confirmed the tumor as a schwannoma.

CONCLUSIONS

The diagnosis of a portal hepatic schwannoma requires immunohistological examinations in addition to multimodality imaging studies to reflect fully the pathohistological characteristics of the tumor.

摘要

背景

肝门部神经鞘瘤是一种罕见的良性肿瘤,由于其罕见性及类似恶性肿瘤的影像学表现,术前难以诊断。我们报告一例肝门部神经鞘瘤,其在计算机断层扫描(CT)上表现为中度强化,在T2加权成像和磁共振胰胆管造影(MRCP)上沿胆管延伸,在正电子发射断层扫描上摄取氟脱氧葡萄糖(FDG)。

病例介绍

一名38岁女性在年度健康检查时通过超声检查发现肝脏有一肿块。CT显示一个边界清晰的肝门部肿瘤,有轻度强化。T2加权成像和MRCP显示一个棒状肿瘤沿肝内胆管延伸,但胆管无扩张。该肿瘤表现为FDG摄取增加,早期和晚期的最大标准化摄取值分别为5.0和6.5。未发现肝内胆管扩张及淋巴结肿大,多模态成像提示为肝门淋巴瘤、胃肠道肿瘤或IgG4相关疾病而非胆管癌。通过内镜超声进行了穿刺活检,免疫组织学证实该肿瘤为神经鞘瘤。

结论

肝门部神经鞘瘤的诊断除多模态影像学检查外,还需要进行免疫组织学检查,以充分反映肿瘤的病理组织学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/8058999/46274fd9b8bc/12876_2021_1767_Fig1_HTML.jpg

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