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单绒毛膜双胎之一宫内胎儿死亡幸存者脑损伤的影像学诊断及法律意义——文献综述

Imaging diagnosis and legal implications of brain injury in survivors following single intrauterine fetal demise from monochorionic twins - a review of the literature.

作者信息

Cruciat Gheorghe, Nemeti Georgiana Irina, Popa-Stanila Roxana, Florian Andreea, Goidescu Iulian Gabriel

机构信息

Obstetrics and Gynecology I, Mother and Child Department, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Department of Radiology, "Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

出版信息

J Perinat Med. 2021 Apr 22;49(7):837-846. doi: 10.1515/jpm-2020-0566. Print 2021 Sep 27.

Abstract

Brain injury of the surviving twin from monochorionic pregnancies following intrauterine fetal demise during the second and third trimesters is a rare but severe complication. Monochorionicity and gestational age at the time of stillbirth seem to be decisive factors in terms of long-term neurologic outcome prediction for the survivor. Magnetic resonance imaging (MRI), diffusion weighted imaging (DWI) in particular, seem to bring the earliest and most accurate diagnosis. Ultrasound detection of brain damage is possible in later stages of fetal brain injury. It is essential to provide early diagnosis and multidisciplinary counsel to the parents to ensure informed decision making. For couples who choose to terminate pregnancy legislation related to late abortion might lead to further distress. Our paper aims to stress the importance of MRI DWI in the evaluation of surviving twins following single intrauterine fetal demise in monochorionic pregnancies and the delicate context of the medical professionals and parents facing this clinical situation, sometimes complicated by legal constraints.

摘要

孕中期和孕晚期单绒毛膜双胎妊娠中,一个胎儿宫内死亡后存活胎儿发生脑损伤是一种罕见但严重的并发症。单绒毛膜性和死产时的孕周似乎是预测存活胎儿长期神经学结局的决定性因素。磁共振成像(MRI),尤其是弥散加权成像(DWI),似乎能带来最早且最准确的诊断。在胎儿脑损伤的后期阶段,超声有可能检测到脑损伤。为父母提供早期诊断和多学科咨询以确保他们能做出明智的决定至关重要。对于选择终止妊娠的夫妇,与晚期堕胎相关的法律可能会导致进一步的痛苦。我们的论文旨在强调MRI DWI在评估单绒毛膜双胎妊娠中单个胎儿宫内死亡后存活双胎方面的重要性,以及医疗专业人员和父母面对这种临床情况时所处的微妙环境,这种情况有时会因法律限制而变得复杂。

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