Sorrenti Sara, Khalil Asma, D'Antonio Francesco, D'Ambrosio Valentina, Zullo Fabrizio, D'Alberti Elena, Derme Martina, Mappa Ilenia, Di Mascio Daniele, Rizzo Giuseppe, Giancotti Antonella
Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00185 Roma, Italy.
Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London SW17 0RE, UK.
J Clin Med. 2024 Nov 30;13(23):7295. doi: 10.3390/jcm13237295.
Twin pregnancies are at increased risk of morbidity and mortality compared to singletons. Among all twins, monochorionic pregnancies are at higher risk of specific and non-specific complications compared to dichorionic pregnancies. Therefore, it is of great importance to properly counsel future parents with monochorionic pregnancies regarding the risks of adverse outcomes and the modalities of monitoring and intervention of the potential complications. Conditions related to the monochorionicity include twin-to-twin transfusion syndrome (TTTS), twin reversed arterial perfusion sequence (TRAP), and twin anemia polycythemia syndrome (TAPS); other complications include selective fetal growth restriction (sFGR) and congenital anomalies. This review aims to summarize the information available in the current literature regarding the complications in monochorionic diamniotic twin pregnancies, including outcomes and guideline recommendations about the clinical surveillance, management, and timing of interventions of these conditions that should be included in counselling in routine clinical practice.
与单胎妊娠相比,双胎妊娠的发病和死亡风险更高。在所有双胎中,与双绒毛膜妊娠相比,单绒毛膜妊娠发生特定和非特定并发症的风险更高。因此,向怀有单绒毛膜妊娠的准父母妥善咨询不良结局的风险以及潜在并发症的监测和干预方式非常重要。与单绒毛膜性相关的情况包括双胎输血综合征(TTTS)、双胎反向动脉灌注序列(TRAP)和双胎贫血-红细胞增多症综合征(TAPS);其他并发症包括选择性胎儿生长受限(sFGR)和先天性异常。本综述旨在总结当前文献中关于单绒毛膜双羊膜囊双胎妊娠并发症的可用信息,包括这些情况的临床监测、管理和干预时机的结局及指南建议,这些应纳入常规临床实践中的咨询内容。