Borgsteede F H, Klaassen C H
Centraal Diergeneeskundig Instituut, afd. Parasitologie, Lelystad.
Tijdschr Diergeneeskd. 1988 Jun 15;113(12):665-72.
The prophylactic effect of an albendazole containing 'pulse release' bolus on gastrointestinal helminth infection in calves during their first grazing season was tested on a farm in the Netherlands in 1986. Thirty calves were divided into two groups of young calves and two of old calves. On being turned out to grass, calves of one of these groups were given a bolus containing 3 x 2 grammes of albendazole, to be released after thirty-one, sixty-two and ninety-three days. The treated young calves showed a much lower egg-output, produced a lower infestation of herbage, displayed significantly lower pepsinogen levels and showed a significantly better gain in weight compared with the untreated young calves. Differences were not observed between the two groups of older calves, probably because of the fact that one of the treated calves had lost the bolus at an earlier stage.
1986年，在荷兰的一个农场对一种含阿苯达唑的“脉冲释放”大丸剂预防犊牛首个放牧季节胃肠道蠕虫感染的效果进行了测试。30头犊牛被分成两组幼犊和两组成年犊牛。这些组中的一组犊牛在开始放牧时被投喂了一粒含3×2克阿苯达唑的大丸剂，该大丸剂在第31、62和93天释放。与未处理的幼犊相比，经处理的幼犊虫卵排出量低得多，牧草感染程度低，胃蛋白酶原水平显著较低，体重增加明显更好。两组成年犊牛之间未观察到差异，可能是因为其中一头经处理的犊牛在早期丢失了大丸剂。
