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观察性骨科研究中的因果语言。

Causal Language in Observational Orthopaedic Research.

机构信息

Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Center for the Advancement of Value in Musculoskeletal Care, Hospital for Special Surgery, and Department of Population Health Sciences, Weill Cornell Medical College, New York, NY.

出版信息

J Bone Joint Surg Am. 2021 Oct 6;103(19):e76. doi: 10.2106/JBJS.20.01921.

Abstract

With the increasing availability of large clinical registries and administrative data sets, observational (i.e., nonexperimental) orthopaedic research is being performed with increased frequency. While this research substantially advances our field, there are fundamental limitations to what can be determined through a single observational study. Avoiding overstatements and misstatements is important for the sake of accuracy, particularly for ensuring that clinical care is not inadvertently swayed by how an observational study is written up and described. We have noticed that causal language is frequently misused in observational orthopaedic research-that is, language that says or implies that 1 variable definitively causes another, despite the fact that causation can generally only be determined with randomization. In this data-backed commentary, we examine the prevalence of causal language in a random sample of 400 observational orthopaedic studies; we found that causal language was misused in 60% of them. We discuss the implications of these results and how to report observational findings more accurately: the word "association" (and its derivatives) can almost always replace or reframe a causal phrase.

摘要

随着大量临床注册和管理数据集的日益普及,观察性(即非实验性)骨科研究的频率也在增加。虽然这项研究极大地推动了我们的领域,但通过单个观察性研究可以确定的内容存在根本的局限性。为了准确性,避免夸大和错误陈述很重要,特别是要确保临床护理不会因观察性研究的编写和描述方式而无意中受到影响。我们注意到,在观察性骨科研究中,因果语言经常被误用——也就是说,尽管因果关系通常只能通过随机化来确定,但语言却表示或暗示一个变量可以明确导致另一个变量。在这份有数据支持的评论中,我们检查了 400 篇随机抽样的观察性骨科研究中因果语言的使用频率;我们发现,其中 60%的研究存在因果语言误用的情况。我们讨论了这些结果的含义以及如何更准确地报告观察性研究结果:“关联”一词(及其派生词)几乎总是可以替代或重新构建因果短语。

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