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[适量食用蔗糖对大鼠肝脏葡萄糖和果糖代谢的影响]

[Effect of moderate amounts of food saccharose on glucose and fructose metabolism in the liver of rats].

作者信息

Gapparov M M, Virovets O A

出版信息

Vopr Pitan. 1988 Mar-Apr(2):32-4.

PMID:3388807
Abstract

Thirty-six male Wistar rats received rations containing 0, 5 or 15% sucrose during 40 days. Significant changes were recorded in the utilization of 6-3H-glucose for the synthesis of lipids and glycogen of the liver. The effect of sucrose feeding on hepatic lipid metabolism depended on the sucrose level: 6-3H-glucose incorporation into liver lipids increased after feeding with the ration containing 5% sucrose, while it was suppressed by 15% sucrose. 6-3H-glucose incorporation into glycogen of the liver was suppressed by both sucrose levels in the ration. U-14C-fructose incorporation into liver glycogen and lipids was not affected by sucrose feeding.

摘要

36只雄性Wistar大鼠在40天内分别摄入含0%、5%或15%蔗糖的日粮。记录到肝脏利用6-3H-葡萄糖合成脂质和糖原的过程有显著变化。蔗糖喂养对肝脏脂质代谢的影响取决于蔗糖水平:喂食含5%蔗糖的日粮后,6-3H-葡萄糖掺入肝脏脂质的量增加,而15%蔗糖则抑制了这种增加。日粮中两种蔗糖水平均抑制了6-3H-葡萄糖掺入肝脏糖原。U-14C-果糖掺入肝脏糖原和脂质不受蔗糖喂养的影响。

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