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[用磷脂浓缩物完全替代饮食中的脂肪对大鼠肝脏线粒体氧化磷酸化及血浆和肝脏脂质组成的影响]

[Effect of the total replacement of fats in the diet with a phospholipid concentrate on oxidative phosphorylation in liver mitochondria and the lipid composition of the plasma and liver in rats].

作者信息

Zhirnov V V, Lavrushenko L F, Tarasenko A P, Kryshevich L P

出版信息

Vopr Pitan. 1988 Mar-Apr(2):34-8.

PMID:3388808
Abstract

Experimental rats were given rations with 100% substitution of fats for phospholipid concentrate, during 1 and 3 months. It was found that such rations produced hypolipidemic and hypocholesterolemic effects, that were most pronounced at the end of the experiment. A control ration with sunflower oil containing high levels of unsaturated fatty acids induced accumulation of lipid peroxides in the hepatic tissue and blood plasma of the animals fed with the ration during 3 months. The ration containing the phospholipid concentrate did not produce such an effect. The data obtained have evidenced a positive influence of the phospholipid concentrate on the lipid metabolism parameters studied.

摘要

实验大鼠在1个月和3个月期间食用完全用磷脂浓缩物替代脂肪的日粮。结果发现,这种日粮产生了降血脂和降胆固醇的作用,在实验结束时最为明显。含高水平不饱和脂肪酸的葵花籽油对照日粮,使食用该日粮3个月的动物肝脏组织和血浆中脂质过氧化物积累。而含磷脂浓缩物的日粮则未产生这种作用。所获得的数据证明了磷脂浓缩物对所研究的脂质代谢参数有积极影响。

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