Synergistic effect of durian fruit rind polysaccharide gel encapsulated prebiotic and probiotic dietary supplements on growth performance, immune-related gene expression, and disease resistance in Zebrafish (.

The present study investigated the effect of polysaccharide gel (PG) extracted from the rind of durian fruit which is encapsulated with as a feed and co-inoculation with in the induction of immune response in after immersion challenge (5 days). The total RBC count, lysozyme activity test, weight, and length analysis revealed that the zebra fishes fed with the PG encapsulated probiotics had more immune induction activity, survival, and growth than the non-encapsulated groups. When the expression of the immune-related genes was measured, the studies revealed the significant upregulation (P < 0 .05) of interleukin 1 beta (Il1b), lysozyme (lyz), tumor necrosis factor-alpha (TNF-α), superoxide dismutase (SOD) genes in fish fed with PG encapsulated probiotics with showed an immense effect on the induction of immune response compared to other feeds.