Department of Orthopaedics, All India Institute of Medical Sciences, Bathinda, Punjab, 151001, India.
Department of Anatomy, All India Institute of Medical Sciences, Rishikesh, India.
Arch Orthop Trauma Surg. 2022 Nov;142(11):3053-3058. doi: 10.1007/s00402-021-03910-3. Epub 2021 Apr 23.
Meniscal allografts are a preferred alternative to menisectomy in cases of irrepairable meniscal tears in young patients. Biological meniscal allograft transplantation requires a cadaveric donor, limiting its availability for transplantation. We are exploring the possibility of using contralateral lateral meniscus for medial meniscal allograft transplantation, as it can be easily procured from proximal tibial cuts from total knee replacement.
Ten paired knees from five formalin-fixed Indian male cadavers were dissected. Outer and inner circumferences of the medial and meniscus, area of the articular surface of the medial tibial plateau covered by the native medial meniscus and transplanted lateral meniscus were noted. Measurements were taken using software ImageJ (National Institute of Health). The mean of the recordings from two independent observers was taken as the final value. Inter-observer and intra-observer reliability were also calculated.
The mean inner circumference of the medial meniscus was significantly larger than the lateral meniscus (p < 0.0001). However, outer circumferences were not significantly different from each other (p = 0.1). Area of the tibial plateau covered by the native medial meniscus was smaller than the area covered by the transplanted lateral meniscus, though the difference was not statistically significant. Inter-observer reliability and intra-observer reliability were good (ICC 0.904 and 0.927, respectively).
Based on measurements of the outer circumference of medial and lateral menisci, lateral meniscal allograft can be matched for transplantation on the contralateral medial side from the donor with same dimensions of the tibial plateau. Further clinical studies are necessary to prove the clinical significance of this cadaveric study.
Diagnostic study.
在年轻患者不可修复的半月板撕裂的情况下，半月板同种异体移植物是半月板切除术的首选替代方法。生物半月板同种异体移植需要尸体供体，这限制了其移植的可用性。我们正在探索使用对侧外侧半月板进行内侧半月板同种异体移植的可能性，因为它可以从全膝关节置换的胫骨近端切口中轻松获得。
从五个福尔马林固定的印度男性尸体中解剖了 10 对膝关节。记录内侧和外侧半月板的外周长和内周长、内侧胫骨平台关节表面被原生内侧半月板和移植的外侧半月板覆盖的区域。使用 ImageJ（美国国立卫生研究院）软件进行测量。取两名独立观察员记录的平均值作为最终值。还计算了观察者间和观察者内的可靠性。
内侧半月板的平均内周长明显大于外侧半月板（p<0.0001）。然而，外周长彼此之间没有显着差异（p=0.1）。被原生内侧半月板覆盖的胫骨平台区域小于被移植的外侧半月板覆盖的区域，但差异无统计学意义。观察者间和观察者内的可靠性都很好（ICC 分别为 0.904 和 0.927）。
根据内侧和外侧半月板外周长的测量，来自同一胫骨平台尺寸供体的对侧内侧侧可以匹配外侧半月板同种异体移植物进行移植。需要进一步的临床研究来证明这项尸体研究的临床意义。
诊断研究。
