School of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, Florida, USA.
J Dermatol. 2021 Aug;48(8):1113-1128. doi: 10.1111/1346-8138.15902. Epub 2021 Apr 22.
Cicatricial alopecias (CA) describes multiple subtypes of hair loss in which the hair follicle is destroyed by an unknown inflammatory mechanism. The main goal of treatment is to stop this inflammatory process and prevent further hair loss; however, there have been occasional reports of hair regrowth following treatment in some subtypes of CA. This review aims to highlight these reports. A total of 71 cases of hair regrowth were found documented in the literature. The treatments used varied widely both between and within each subtype of alopecia. This review highlights that regrowth is possible in at least a subset of patients with cicatricial alopecia; however, the mechanism by which this occurs has yet to be elucidated.
瘢痕性脱发（CA）描述了多种类型的脱发，其中毛囊被未知的炎症机制破坏。治疗的主要目标是阻止这种炎症过程并防止进一步的脱发；然而，在某些 CA 亚型的治疗后偶尔有报道称头发再生。本综述旨在强调这些报道。在文献中总共发现了 71 例头发再生的病例报告。所使用的治疗方法在每种脱发亚型内和之间差异很大。本综述强调，在至少一部分瘢痕性脱发患者中，头发再生是可能的；然而，其发生的机制尚未阐明。
