Mutayoba B M, Gombe S, Waindi E N, Kaaya G P
Reproductive Biology Unit, NCRR, University of Nairobi, Kenya.
Acta Endocrinol (Copenh). 1988 Apr;117(4):477-84. doi: 10.1530/acta.0.1170477.
Adult normocyclic female goats experimentally infected with Trypanosoma congolense developed irregular and shorter estrous cycles before complete cessation at the fourth cycle post-infection. This was followed within a month by a decline in the mean plasma progesterone and estradiol-17 beta levels. The peak luteal progesterone as well as pre-ovulatory estradiol-17 beta level declined progressively from the second to the fourth cycle post-infection. The ovaries became atretic with reduced numbers of primordial and primary follicles. The larger follicles became atretic at the tertiary stage with subsequent lack of corpora lutea formation. The rapidity of ovarian dysfunction appeared to be related to the degree of susceptibility of the individual infected goats.
实验性感染刚果锥虫的成年正常周期雌性山羊，在感染后第四个周期完全停止发情之前，发情周期变得不规律且缩短。随后在一个月内，血浆孕酮和雌二醇-17β的平均水平下降。从感染后第二个周期到第四个周期，黄体期孕酮峰值以及排卵前雌二醇-17β水平逐渐下降。卵巢出现闭锁，原始卵泡和初级卵泡数量减少。较大的卵泡在三级阶段出现闭锁，随后缺乏黄体形成。卵巢功能障碍的快速程度似乎与个体感染山羊的易感性程度有关。
