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糖尿病大鼠的肌肉胶原蛋白含量

Muscle collagen content in diabetic rats.

作者信息

al-Zaid N S

机构信息

Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Arabian Gulf.

出版信息

Acta Physiol Hung. 1988;71(1):41-3.

PMID:3389156
Abstract

Collagen content (mg/dl of dry weight) was measured biochemically in the extensor digitorum longus and the soleus muscle in rats. Comparison of muscles from diabetic (induced by intraperitoneal streptozotocin injection /60 mg/kg body weight/) and non diabetic controls showed an increase in the collagen content of the extensor digitorum longus, and little change in the soleus. The differences did not attain statistical significance indicating that the accelerated collagen ageing attributed to diabetes may not necessarily be true in all tissues.

摘要

通过生化方法测量了大鼠趾长伸肌和比目鱼肌中的胶原蛋白含量(毫克/干重分升)。对糖尿病大鼠(通过腹腔注射链脲佐菌素诱导,剂量为60毫克/千克体重)和非糖尿病对照组的肌肉进行比较,结果显示趾长伸肌中的胶原蛋白含量增加,而比目鱼肌中的变化很小。这些差异未达到统计学显著性,表明归因于糖尿病的胶原蛋白加速老化不一定在所有组织中都成立。

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