Szelényi Z, Péczely P, Vadócz E
Institute of Physiology, University of Veterinary Science, Budapest, Hungary.
Acta Physiol Hung. 1988;71(1):69-75.
Forced moulting has been induced in domestic hens by progesterone treatment (5 mg/day) for 25 days. Moult happened between the 11th and 19th day after the first treatment. Endocrine changes were followed during the moult by blood sampling in one week intervals. At the time of the last sampling, new egg laying cycle was initiated in all birds. Plasma progesterone concentration increased significantly in response to the treatment then tended to decrease. Oestrone and testosterone levels were the lowest during the period when feather loss was most intensive and increased in the course of feathering. This increase was significant in the case of oestrone. The level of 17-beta-oestradiol did not vary during moult induced by progesterone treatment. Plasma concentration of thyroxine significantly increased during feather loss, showing a maximum in the second and/or third week after the beginning of the treatment, while it decreased when feather growth had begun. Plasma triiodothyronine as well as corticosterone levels were the highest during the latest phase of moult, at the time of feather outgrowing. It has been supposed that moulting would be initiated in response to the synergistic effect on feather follicles of progesterone and thyroxine, which was stimulated by the progesterone treatment. The atrophic stage of the ovary suggested that progesterone was probably of adrenal origin. It was assumed that triiodothyronine and oestrone were responsible for controlling feather outgrowth.
通过给蛋鸡注射孕酮（5毫克/天），持续25天，诱导其强制换羽。首次治疗后的第11天至第19天开始换羽。在换羽期间，每隔一周采血一次，跟踪内分泌变化。在最后一次采样时，所有鸡都开始了新的产蛋周期。血浆孕酮浓度在治疗后显著升高，随后趋于下降。雌酮和睾酮水平在羽毛脱落最剧烈的时期最低，并在羽毛生长过程中升高。雌酮的升高具有显著性。在孕酮诱导的换羽过程中，17-β-雌二醇水平没有变化。血浆甲状腺素浓度在羽毛脱落期间显著升高，在治疗开始后的第二周和/或第三周达到最高，而在羽毛开始生长时下降。血浆三碘甲状腺原氨酸和皮质酮水平在换羽的最后阶段，即羽毛长出时最高。据推测，孕酮处理刺激了孕酮和甲状腺素对毛囊的协同作用，从而启动了换羽过程。卵巢的萎缩阶段表明，孕酮可能起源于肾上腺。据推测，三碘甲状腺原氨酸和雌酮负责控制羽毛的生长。
