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表现为急性肾损伤伴严重高血压及活动性尿沉渣的急性重度肾动脉狭窄

Acute Severe Renal Artery Stenosis Presenting as Acute Kidney Injury With Severe Hypertension and Active Urine Sediment.

作者信息

Jegatheswaran Januvi, Hadziomerovic Adnan, Ruzicka Marcel

机构信息

Division of Nephrology, Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.

Department of Radiology, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

Can J Cardiol. 2021 Oct;37(10):1671-1673. doi: 10.1016/j.cjca.2021.04.008. Epub 2021 Apr 20.

DOI:10.1016/j.cjca.2021.04.008
PMID:33892127
Abstract

We present a case of severe renal artery stenosis that mimicked rapidly progressive glomerulonephritis with acute kidney injury, active urine sediments, and severe hypertension. Simultaneous presence of secondary hyperaldosteronism and hypokalemia prompted renal angiography and subsequent renal artery angioplasty and stenting, leading to rapid resolution of acute kidney injury, proteinuria, and hypertension. This case emphasises the importance and benefits of prompt diagnosis and revascularisation of acute severe renal artery stenosis in a patient with history of atherosclerotic renovascular disease presenting with sudden onset of severe hypertension and acute kidney injury with active urine sediment mimicking rapidly progressive glomerulonephritis.

摘要

我们报告一例严重肾动脉狭窄病例,该病例表现为类似急进性肾小球肾炎,伴有急性肾损伤、活动性尿沉渣及严重高血压。继发性醛固酮增多症和低钾血症同时存在促使进行肾血管造影,随后进行肾动脉血管成形术和支架置入术,从而使急性肾损伤、蛋白尿和高血压迅速得到缓解。该病例强调了对于有动脉粥样硬化性肾血管疾病病史、突发严重高血压及伴有活动性尿沉渣的急性肾损伤(类似急进性肾小球肾炎)的患者,及时诊断并对急性严重肾动脉狭窄进行血运重建的重要性和益处。

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Can J Cardiol. 2021 Oct;37(10):1671-1673. doi: 10.1016/j.cjca.2021.04.008. Epub 2021 Apr 20.
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When Revascularization May Be Appropriate in Atherosclerotic Renal Artery Stenosis.在动脉粥样硬化性肾动脉狭窄中何时血管重建术可能适用
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Urantide alleviates atherosclerosis-related liver and kidney injury via the Wnt/β-catenin signaling pathway in ApoE(-/-) mice.乌瑞替肽通过 Wnt/β-连环蛋白信号通路减轻载脂蛋白 E 基因敲除小鼠的动脉粥样硬化相关肝肾脏损伤。
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