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长腿兀鹫()中的恶性黑素瘤:临床和组织学病变的特征。

Malignant Melanoma in a Long-legged Buzzard (): Characterization of Clinical and Histologic Lesions.

机构信息

ZooParc de Beauval & Beauval Nature, Route du Blanc, 41110 Saint Aignan sur Cher, France,

ZooParc de Beauval & Beauval Nature, Route du Blanc, 41110 Saint Aignan sur Cher, France.

出版信息

J Avian Med Surg. 2021 Apr;35(1):80-85. doi: 10.1647/1082-6742-35.1.80.

Abstract

A 17-year-old, male long-legged buzzard () presented for acute lethargy and black gelatinous tissue in both nostrils. Despite intensive care, the bird died within 2 days. A postmortem computed tomographic scan of the head revealed a complete obstruction of the rostral infraorbital sinus, later confirmed by necropsy. Postmortem examination also highlighted multifocal, black, infiltrating nodules of various sizes (2 mm to 2 cm in diameter) in almost all internal organs: lungs, heart (pericardium, myocardium, endocardium), kidneys, pancreas, adrenals, muscles, and bones (periosteum and medulla). Histologically, the nodules were composed of anaplastic cells containing abundant melanin pigment, consistent with a disseminated melanoma. Malignant melanomas are aggressive neoplasms frequently reported in mammals but rarely found in avian species. In Accipitridae and Falconidae, only 2 cases have been reported.

摘要

一只 17 岁雄性长腿兀鹫出现急性嗜睡和两个鼻孔中都有黑色胶状组织。尽管进行了强化护理,这只鸟还是在 2 天内死亡。头部的死后计算机断层扫描显示眶下窦的前部完全阻塞,后来通过尸检得到证实。死后检查还突出显示了几乎所有内部器官中存在多发性、黑色、浸润性的各种大小的结节(直径 2 毫米至 2 厘米):肺、心脏(心包、心肌、心内膜)、肾脏、胰腺、肾上腺、肌肉和骨骼(骨膜和骨髓)。组织学上,这些结节由含有大量黑色素的异形细胞组成,符合弥散性黑色素瘤。恶性黑色素瘤是一种侵袭性肿瘤,在哺乳动物中经常被报道,但在鸟类中很少见。在鹰科和隼科中,仅报告了 2 例。

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