Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Division of Neurointerventional Radiology, Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.
Interv Neuroradiol. 2021 Dec;27(6):821-827. doi: 10.1177/15910199211013195. Epub 2021 Apr 23.
Flow diversion is commonly used to treat intracranial aneurysms in various regions of the cerebral vasculature, but is only approved for use in the internal carotid arteries. Treatment of distal PICA aneurysms with PED is sometimes performed but has not been well studied. Here, we report our experience with flow diversion of distal PICA aneurysms with PED.
Clinical and angiographic data of eligible patients was retrospectively obtained and assessed for key demographic characteristics and clinical and angiographic outcomes. Principal outcomes included rates of aneurysm occlusion, ischemic or hemorrhagic complication, technical complication, and in-stent stenosis.
Three female and 2 male patients underwent placement of PED in the PICA for treatment of 5 distal PICA aneurysms. Clinical and angiographic follow-up was obtained for all patients. Complete aneurysm occlusion was observed in 100% (5/5) of treated aneurysms at 6 month and longest angiographic follow-up. While there were no ischemic or device-related complications, delayed hemorrhagic complications occurred in 20% (1/5) of patients.
Pipeline embolization of distal PICA aneurysms can be performed in select patients. Further study is necessary in larger cohorts to better define clinical scenarios in which flow diversion in the distal PICA should be considered.
血流导向装置常用于治疗颅内血管的不同部位的颅内动脉瘤,但仅被批准用于颈内动脉。有时会对 PICA 远端动脉瘤进行 PED 治疗,但尚未得到充分研究。在此,我们报告使用 PED 治疗 PICA 远端动脉瘤的经验。
回顾性获得符合条件的患者的临床和血管造影数据,并评估其关键人口统计学特征以及临床和血管造影结果。主要结局包括动脉瘤闭塞率、缺血性或出血性并发症、技术并发症和支架内狭窄率。
3 名女性和 2 名男性患者因 5 个 PICA 远端动脉瘤而行 PED 置入治疗。所有患者均获得了临床和血管造影随访。在 6 个月和最长的血管造影随访时,100%(5/5)的治疗动脉瘤完全闭塞。虽然没有缺血性或器械相关并发症,但 20%(1/5)的患者发生了迟发性出血性并发症。
在选择的患者中可以进行 PICA 远端动脉瘤的 Pipeline 栓塞治疗。需要在更大的队列中进行进一步研究,以更好地确定应考虑在 PICA 远端进行血流导向装置治疗的临床情况。