Deora Harsh, Nayak Nitish, Dixit Priyadarshi, Vikas V, Rao K V L Narasinga, Pruthi Nupur, Srinivas Dwarakanath, Shukla Dhaval P, Bhat Dhananjay I, Malla Bhaskara Rao, Devi Bhagvatula Indira, Somanna Sampath
Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
J Neurosci Rural Pract. 2020 Jan;11(1):34-43. doi: 10.1055/s-0039-3399486. Epub 2020 Jan 27.
Posterior inferior cerebellar artery (PICA) is a tortuous, variable, and uncommon site for aneurysms. Surgical management of PICA aneurysms involves careful selection of approach based on the location of the aneurysm and meticulous dissection of the neurovascular structures and perforators. We did a retrospective review of all the PICA aneurysms operated at our institute in the past 10 years along with the site, presentation, and approach used for the same. Preoperative World Federation of Neurosurgical Society scores and follow-up modified Rankin scores (mRS) were also evaluated. During the same period, data for intervention cases of PICA aneurysm were also collected with follow-ups for a comparative analysis. A total of 20 patients with 21 PICA aneurysms were reviewed. All the reviewed cases presented with subarachnoid hemorrhage, and the most common location was the lateral medullary segment and vertebral artery (VA)-PICA junction. Midline approaches were used for distal PICA cases, with far-lateral approach reserved for anterior medullary/VA-PICA junction. No lower cranial nerve palsies were recorded at follow-up. Four cases needed cerebrospinal fluid diversion and two developed cerebellar infarcts. All cases were mRS 0 to 2 at follow-up. Our series compares well with some of the larger surgical series of PICA aneurysms. This may be due to early referral patterns and early surgery (<24 hours) policy at our institution. Anatomical knowledge of PICA anatomy and sound perioperative management are keys to good outcomes in these cases.
小脑后下动脉(PICA)走行迂曲、形态多变,是动脉瘤的罕见发病部位。PICA动脉瘤的手术治疗需要根据动脉瘤的位置仔细选择手术入路,并对神经血管结构和穿支进行精细解剖。
我们对本机构过去10年手术治疗的所有PICA动脉瘤病例进行了回顾性研究,包括动脉瘤的位置、临床表现及所采用的手术入路。同时评估了术前世界神经外科联盟(WFNS)评分和随访时的改良Rankin评分(mRS)。在此期间,还收集了PICA动脉瘤介入治疗病例的数据并进行随访,以便进行对比分析。
共回顾了20例患者的21个PICA动脉瘤。所有回顾病例均表现为蛛网膜下腔出血,最常见的位置是延髓外侧段和椎动脉(VA)-PICA交界处。对于PICA远端动脉瘤病例采用中线入路,而延髓前部/VA-PICA交界处动脉瘤则采用远外侧入路。随访时未记录到低位颅神经麻痹。4例患者需要进行脑脊液分流,2例发生小脑梗死。所有病例随访时mRS评分均为0至2分。
我们的系列病例与一些较大规模的PICA动脉瘤手术系列病例相比效果良好。这可能得益于我们机构早期的转诊模式和早期手术(<24小时)策略。熟悉PICA的解剖知识并进行完善的围手术期管理是这些病例取得良好预后的关键。