Faculty of Medicine and Health Sciences (Dentistry), University of Barcelona, Barcelona, Spain.
Department of Odontoestomatology, Faculty of Medicine and Health Sciences (Dentistry), Bellvitge Campus, University of Barcelona, Barcelona, Spain.
BMC Oral Health. 2021 Apr 23;21(1):204. doi: 10.1186/s12903-021-01566-4.
The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. It's important to know the characteristics present in these lesions and possible effects on the prognosis of dental implants.
An electronic search without time restrictions was done in the databases: PubMed/Medline. With the keywords "Granuloma" OR "Granuloma, Giant Cell" OR "peripheral giant cell" OR "Granuloma, Pyogenic" AND "Dental implants" OR "Oral implants".
After applying the inclusion and exclusion criteria, a total of 20 articles were included, which reported 32 lesions (10 pyogenic granulomas, 21 peripheral giant cell granulomas and one peripheral giant cell granuloma combined with peripheral ossifying fibroma, all associated with implants). According to our review, these lesions are more frequent in males and in the posterior region of the mandible. Both excision and curettage of the lesion, compared to only excision, presented similar recurrences (40%). Explantation of the implant was performed in 41% of cases without additional recurrences. The results are not statistically significant when comparing one lesion to the other in terms of explantation (p = 0.97), recurrence (p = 0.57) or bone loss (p = 0.67).
The main therapeutic approach is tissue excision. The lesions show a high recurrence rate (34.4%), which often requires explantation of the associated implant. This recurrence rate is not affected by curettage after excision.
本研究旨在评估与牙种植体相关的外周性骨巨细胞瘤和化脓性肉芽肿的文献复发率。了解这些病变的特征及其对牙种植体预后的可能影响非常重要。
无时间限制地在数据库 PubMed/Medline 中进行电子搜索。使用关键词“Granuloma”或“Granuloma, Giant Cell”或“peripheral giant cell”或“Granuloma, Pyogenic”和“Dental implants”或“Oral implants”。
应用纳入和排除标准后,共纳入 20 篇文章,共报道 32 例病变(10 例化脓性肉芽肿、21 例外周性骨巨细胞瘤和 1 例外周性骨巨细胞瘤合并外周骨化纤维瘤,均与种植体相关)。根据我们的回顾,这些病变在男性和下颌后区更为常见。与单纯切除相比,切除和刮除病变的复发率相似(40%)。在 41%的病例中,在未出现额外复发的情况下,对种植体进行了取出。在比较不同病变的种植体取出(p=0.97)、复发(p=0.57)或骨丢失(p=0.67)方面,结果无统计学意义。
主要的治疗方法是组织切除。病变的复发率较高(34.4%),常需要取出相关的种植体。切除后刮除并不能降低复发率。