Nguyen Quynh, Meng Eric, Berube Joel, Bergstrom Richard, Lam Wing
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Division of Anesthesiology & Pain Medicine, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2S2, Canada.
J Cardiothorac Surg. 2021 Apr 23;16(1):109. doi: 10.1186/s13019-021-01493-z.
Preoperative anemia and transfusion are associated with worse outcomes. This study aims to identify the prevalence of preoperative anemia, transfusion rates on surgery day, and predictors of transfusion in elective cardiac surgery patients at our centre. We also aim to evaluate our preoperative intervention program, and examine the intervention window for anemia before surgery.
This study included 797 adult patients who underwent elective cardiac surgery at a tertiary hospital. Multivariable logistic regression analysis was used to identify predictors of transfusion on surgery day.
Preoperative anemia was present in 15% of patients. Anemic patients had a significantly higher transfusion rate at 53% compared to 10% in non-anemic patients. Hemoglobin concentration, estimated glomerular filtration rate (eGFR), body surface area (BSA), and total cardiopulmonary bypass time were predictive of transfusion on surgery day. Patients had a median of 7 days between initial visit and surgery day, however, referral to the blood conservation clinic was only done for 8% of anemic patients and treatment was initiated in 3% of anemic patients. Among the 3 anemic patients who received treatment, 2 did not require blood transfusion on surgery day.
Preoperative anemia is present in 15% of patients at our centre and these patients have 53% transfusion rates on surgery day. Hemoglobin concentration, eGFR, BSA, and total cardiopulmonary bypass time were predictors of transfusion on surgery day. Patients had a median of 7 days between initial visit and surgery day. Referral and anemia treatment were infrequently initiated in preoperative anemic patient.
术前贫血和输血与较差的预后相关。本研究旨在确定我院择期心脏手术患者术前贫血的患病率、手术当天的输血率以及输血的预测因素。我们还旨在评估我们的术前干预方案,并研究术前贫血的干预窗口期。
本研究纳入了一家三级医院797例接受择期心脏手术的成年患者。采用多变量逻辑回归分析确定手术当天输血的预测因素。
15%的患者存在术前贫血。贫血患者的输血率显著更高,为53%,而非贫血患者为10%。血红蛋白浓度、估计肾小球滤过率(eGFR)、体表面积(BSA)和体外循环总时间是手术当天输血的预测因素。患者从初次就诊到手术当天的中位时间为7天,然而,只有8%的贫血患者被转诊至血液保护门诊,3%的贫血患者开始接受治疗。在3例接受治疗的贫血患者中,2例在手术当天不需要输血。
我院15%的患者存在术前贫血,这些患者在手术当天的输血率为53%。血红蛋白浓度·eGFR、BSA和体外循环总时间是手术当天输血的预测因素。患者从初次就诊到手术当天的中位时间为7天。术前贫血患者很少被转诊和开始贫血治疗。