Aalberts J S, Weegels P L, van der Heijden L, Borst M H, Burema J, Hautvast J G, Kouwenhoven T
Department of Human Nutrition, Agricultural University, Wageningen, The Netherlands.
Am J Clin Nutr. 1988 Jul;48(1):131-8. doi: 10.1093/ajcn/48.1.131.
After an initial 4-wk period, 36 healthy male subjects aged 19-28 y (14 lactoovovegetarians and 22 omnivores) were given a supplement to their usual diet of 27.9 mmol calcium/d for 5 wk. During this period 22 blood pressure measurements were taken and 30 24-h urine specimens and 15 24-h dietary records were obtained. Base-line blood pressures did not differ significantly between vegetarians and omnivores (118.3/59.3 and 119.5/60.7, respectively). At the end of the supplementation period there was a decrease in diastolic blood pressure of 1.4 mm Hg (p less than 0.10) and an unexpected increase in systolic blood pressure of 2.1 mm Hg (p less than 0.01) in the omnivores. Although not significant, the same trends were observed in the vegetarians. In both groups Ca and magnesium excretions increased significantly and phosphorus excretion decreased significantly. Blood pressure of normotensive subjects with high basal Ca intake may not be sensitive to Ca supplementation.
在最初的4周之后,36名年龄在19 - 28岁的健康男性受试者(14名乳蛋素食者和22名杂食者)在其日常饮食基础上,连续5周每天补充27.9毫摩尔钙。在此期间,进行了22次血压测量,并收集了30份24小时尿液样本和15份24小时饮食记录。素食者和杂食者的基线血压无显著差异(分别为118.3/59.3和119.5/60.7)。在补充期结束时,杂食者的舒张压下降了1.4毫米汞柱(p < 0.10),而收缩压意外升高了2.1毫米汞柱(p < 0.01)。虽然不显著,但素食者也观察到了相同趋势。两组中钙和镁的排泄量均显著增加,磷的排泄量显著减少。基础钙摄入量高的血压正常受试者的血压可能对补钙不敏感。