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癌症愈合缓慢还是诊断缓慢?

Slow to heal or slow to diagnose cancer?

机构信息

Oral and Maxillofacial Surgery, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.

Oral and Maxillofacial Surgery, Royal United Hospitals Bath Foundation Trust, Bath, UK.

出版信息

Br Dent J. 2021 Apr;230(8):518-522. doi: 10.1038/s41415-021-2837-y. Epub 2021 Apr 23.

Abstract

There are around 8,500 new cases of oral squamous cell carcinoma (SCC) diagnosed in the UK each year and the incidence appears to be increasing. Although surgical and non-surgical treatment options have improved significantly in the last few decades, five-year survival has not, with an average five-year survival of 56% in the UK. Providing patients have access, there are frequent opportunities for oral cancer screening by their general dental practitioner. We present two cases of SCC managed in our department, both of whom were referred following a protracted period of review in general dental practice, where the initial 'benign diagnoses' were not re-evaluated during this time. This delay can considerably impact on patient outcomes, including survival. We outline each patient's clinical course, and key learning points to help dental practitioners detect lesions that require prompt referral to the oral and maxillofacial service for urgent investigation.

摘要

英国每年约有 8500 例新诊断的口腔鳞状细胞癌(SCC)病例,且发病率似乎呈上升趋势。尽管在过去几十年中,手术和非手术治疗选择有了显著改善,但五年生存率并没有提高,英国的平均五年生存率为 56%。只要患者能够获得治疗,他们的普通牙科医生就有频繁的机会进行口腔癌筛查。我们在本科室管理了两例 SCC 病例,这两例都是在普通牙科实践中经过长时间的复查后转诊过来的,在这段时间里,最初的“良性诊断”并没有重新评估。这种延迟会对患者的预后产生重大影响,包括生存率。我们概述了每位患者的临床病程和关键学习要点,以帮助牙科医生发现需要及时转介到口腔颌面服务部门进行紧急检查的病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/d6576b527360/41415_2021_2837_Fig1_HTML.jpg

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