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癌症愈合缓慢还是诊断缓慢?

Slow to heal or slow to diagnose cancer?

机构信息

Oral and Maxillofacial Surgery, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.

Oral and Maxillofacial Surgery, Royal United Hospitals Bath Foundation Trust, Bath, UK.

出版信息

Br Dent J. 2021 Apr;230(8):518-522. doi: 10.1038/s41415-021-2837-y. Epub 2021 Apr 23.

DOI:10.1038/s41415-021-2837-y
PMID:33893424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8063191/
Abstract

There are around 8,500 new cases of oral squamous cell carcinoma (SCC) diagnosed in the UK each year and the incidence appears to be increasing. Although surgical and non-surgical treatment options have improved significantly in the last few decades, five-year survival has not, with an average five-year survival of 56% in the UK. Providing patients have access, there are frequent opportunities for oral cancer screening by their general dental practitioner. We present two cases of SCC managed in our department, both of whom were referred following a protracted period of review in general dental practice, where the initial 'benign diagnoses' were not re-evaluated during this time. This delay can considerably impact on patient outcomes, including survival. We outline each patient's clinical course, and key learning points to help dental practitioners detect lesions that require prompt referral to the oral and maxillofacial service for urgent investigation.

摘要

英国每年约有 8500 例新诊断的口腔鳞状细胞癌(SCC)病例,且发病率似乎呈上升趋势。尽管在过去几十年中,手术和非手术治疗选择有了显著改善,但五年生存率并没有提高,英国的平均五年生存率为 56%。只要患者能够获得治疗,他们的普通牙科医生就有频繁的机会进行口腔癌筛查。我们在本科室管理了两例 SCC 病例,这两例都是在普通牙科实践中经过长时间的复查后转诊过来的,在这段时间里,最初的“良性诊断”并没有重新评估。这种延迟会对患者的预后产生重大影响,包括生存率。我们概述了每位患者的临床病程和关键学习要点,以帮助牙科医生发现需要及时转介到口腔颌面服务部门进行紧急检查的病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/df6a19545a3d/41415_2021_2837_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/d6576b527360/41415_2021_2837_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/e697ac5cad49/41415_2021_2837_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/a0d1cf8bad52/41415_2021_2837_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/df6a19545a3d/41415_2021_2837_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/d6576b527360/41415_2021_2837_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/e697ac5cad49/41415_2021_2837_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/a0d1cf8bad52/41415_2021_2837_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aac2/8063191/df6a19545a3d/41415_2021_2837_Fig4_HTML.jpg

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本文引用的文献

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The synergistic effect of tobacco and alcohol consumption on oral squamous cell carcinoma: a systematic review and meta-analysis.烟草和酒精消费对口腔鳞状细胞癌的协同作用:系统评价和荟萃分析。
Clin Oral Investig. 2019 Jul;23(7):2849-2859. doi: 10.1007/s00784-019-02958-1. Epub 2019 May 20.
2
Scottish referral guidelines for suspected cancer.苏格兰疑似癌症转诊指南。
Br Dent J. 2019 Apr;226(7):472-473. doi: 10.1038/s41415-019-0214-x.
3
Diagnosis and referral delays in primary care for oral squamous cell cancer: a systematic review.
口腔鳞状细胞癌初级保健中的诊断和转诊延误:系统评价。
Br J Gen Pract. 2019 Feb;69(679):e112-e126. doi: 10.3399/bjgp18X700205. Epub 2018 Nov 19.
4
Mouth cancer: presentation, detection and referral in primary dental care.口腔癌:初级牙科保健中的表现、检测和转诊。
Br Dent J. 2018 Nov 9;225(9):833-840. doi: 10.1038/sj.bdj.2018.931.
5
The pathology of oral cancer.口腔癌的病理学。
Br Dent J. 2018 Nov 9;225(9):841-847. doi: 10.1038/sj.bdj.2018.926.
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The changing aetiology of head and neck squamous cell cancer: A tale of three cancers?头颈部鳞状细胞癌不断变化的病因:三种癌症的故事?
Clin Otolaryngol. 2018 Aug;43(4):999-1003. doi: 10.1111/coa.13144. Epub 2018 Jun 13.
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The relative length of the patient and the primary care interval in patients with 28 common and rarer cancers.28种常见及罕见癌症患者的患者相对长度及初级保健间隔时间。
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