Mahidol University Health Technology Assessment (MUHTA) Graduate Program, Bangkok, Thailand.
Pharmacy Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Obes Surg. 2021 Jul;31(7):3279-3290. doi: 10.1007/s11695-021-05415-9. Epub 2021 Apr 24.
This systematic review aimed to comprehensively synthesize cost-effectiveness evidences of bariatric surgery by pooling incremental net monetary benefits (INB). Twenty-eight full economic evaluation studies comparing bariatric surgery with usual care were identified from five databases. In high-income countries (HICs), bariatric surgery was cost-effective among mixed obesity group (i.e., obesity with/without diabetes) over a 10-year time horizon (pooled INB = $53,063.69; 95% CI $42,647.96, $63,479.43) and lifetime horizon (pooled INB = $101,897.96; 95% CI $79,390.93, $124,404.99). All studies conducted among obese with diabetes reported that bariatric surgery was cost-effective. Also, the pooled INB for obesity with diabetes group over lifetime horizon in HICs was $80,826.28 (95% CI $32,500.75, $129,151.81). Nevertheless, no evidence is available in low- and middle-income countries.
本系统评价旨在通过汇总增量净货币效益（INB），全面综合肥胖症手术的成本效益证据。从五个数据库中确定了 28 项比较肥胖症手术与常规护理的全经济评估研究。在高收入国家（HIC）中，肥胖症手术在 10 年时间范围内（汇总 INB = 53063.69 美元；95%CI 42647.96，63479.43）和终身时间范围内（汇总 INB = 101897.96 美元；95%CI 79390.93，124404.99）对混合肥胖组（即患有/不患有糖尿病的肥胖症）具有成本效益。所有在患有糖尿病的肥胖症患者中进行的研究都表明，肥胖症手术具有成本效益。此外，HIC 中糖尿病肥胖症患者的终身时间范围内的汇总 INB 为 80826.28 美元（95%CI 32500.75，129151.81）。然而，在中低收入国家没有相关证据。
