In the recent years, migraine has been widely studied by scholars from all over the world. This study aimed to use scientometric methods to identify research frontiers and development trends in the field of migraine research. We used the Web of Science (WoS) core collection database to collect articles and reviews related to migraine published from 2010 to 2019 on March 25, 2020. VOSviewer, CiteSpace, and Excel were used for the scientometric analysis. A total of 6,357 publications (including 5,203 articles and 1,154 reviews) were identified. The United States published the most publications (n=2,151, 33.84%). Albert Einstein College of Medicine contributed the most publications (n=220, 3.46%). Cephalalgia was found to be the core journal with the most publications (n=766, impact factor 2019 =4.868) as well as the most co-citations (n=35,535). Lipton RB authored the most publications (n=159, 2.50%), while Silberstein SD received the most co-citations (n=4,215). The critical topics were causes and pathophysiological mechanisms, epidemiological characteristics, diagnostic criteria, treatment and prevention drugs, and migraine-related genes. Through the use of scientometric methods, this article has mapped the knowledge landscape of migraine research over the past decade. By showing the overall status of the field, it provides a useful reference for future research.