Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Interventional Cardiology, Sones Cardiac Catheterization Laboratories, Interventional Cardiology Fellowship, Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Cardiol Clin. 2021 May;39(2):221-232. doi: 10.1016/j.ccl.2021.01.006. Epub 2021 Mar 23.
Mitral valve anatomy is complex, and one size does not fit all. More recently, percutaneous mitral valve interventions have revolutionized the management of primary and secondary mitral regurgitation (MR). However, edge-to-edge leaflet repair is not suitable for a large proportion of individuals including those with a failing bioprosthetic mitral valve/annuloplasty ring, and patients with significant mitral annular calcification resulting in mixed mitral valve disease/mitral stenosis. For this high risk cohort, transcatheter mitral valve replacement seems to be an attractive alternative.
二尖瓣解剖结构复杂，并非一种尺寸适合所有患者。最近，经皮二尖瓣介入治疗已经彻底改变了原发性和继发性二尖瓣反流（MR）的治疗方式。然而，瓣叶对合缘修复并不适用于很大一部分人群，包括生物瓣置换/瓣环成形术后出现功能障碍的患者，以及存在严重二尖瓣环钙化导致混合性二尖瓣疾病/二尖瓣狭窄的患者。对于这一高危患者群体，经导管二尖瓣置换术似乎是一种颇具吸引力的替代方法。
