Department of Anesthesia, Critical Care and Pain Medicine, 2348Massachusetts General Hospital, Boston, MA, USA.
J Med Biogr. 2023 Feb;31(1):10-15. doi: 10.1177/09677720211002205. Epub 2021 Apr 24.
Ernest Shackleton, an accomplished Antarctic explorer, developed a life-threatening illness during the Discovery Antarctic expedition of 1901-4. His documented signs and symptoms included inflamed gums attributed to scurvy, severe dyspnea, and exercise intolerance, presenting in a setting of nutritional deficiency. Physical examinations at a later date, also following a prolonged diet of limited fresh food, revealed a pulmonary systolic murmur. Thiamine deficiency with cardiomyopathy, either alone or subsequently exacerbated by advanced scurvy, may have been a prominent cause of Shackleton's condition.
欧内斯特·沙克尔顿（Ernest Shackleton）是一位杰出的南极探险家，他在 1901-1904 年的“发现”号南极探险中患上了危及生命的疾病。他的病历记录的体征和症状包括坏血病引起的牙龈发炎、严重呼吸困难和运动不耐受，这些都发生在营养缺乏的情况下。在后来的检查中，在长期食用有限的新鲜食物后，还发现了肺动脉收缩期杂音。无论是单独存在还是随后因严重坏血病而恶化的硫胺素缺乏伴心肌病，都可能是沙克尔顿病情的主要原因。
