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先天性紫绀型心脏病患儿的骨密度评估。

Assessment of bone mineral density in children with congenital cyanotic heart disease.

机构信息

Department of Pediatrics, Mansoura University, Mansoura, Egypt.

出版信息

Cardiol Young. 2022 Jan;32(1):71-76. doi: 10.1017/S1047951121001554. Epub 2021 Apr 26.

DOI:10.1017/S1047951121001554
PMID:33896435
Abstract

BACKGROUND

Cyanotic CHD is one of many disorders in paediatrics that influence the health of children in different clinical aspects. One of the fundamental aspects that may be affected is bone mineral density.

OBJECTIVES

The aim of our study is to assess bone mineral density in children with congenital cyanotic heart disease of different anatomical diagnoses.

DESIGN/METHODS: Cross-sectional, observational study included 39 patients (20 males) with congenital cyanotic heart disease of different anatomical diagnoses following with the cardiology clinic in Mansoura University children's hospital. All patients were subjected to anthropometric measures, oxygen saturation assessment, and lumber bone mineral density using dual-energy X-ray absorptiometry.

RESULTS

Six patients (15.4%) out of the 39 included patients showed bone mineral density reduction, 13 patients (33.3%) showed bone mineral density with Z-score between -1 and -2, while 20 patients (51.3%) showed bone mineral density with Z-score more than -1.

CONCLUSION

Low bone mineral density can be found in children with cyanotic CHD, making it important to consider bone mineral density assessment and early treatment if needed to avoid further complications.

摘要

背景

紫绀型先天性心脏病是儿科中影响儿童多个临床方面健康的众多疾病之一。其中一个可能受到影响的基本方面是骨矿物质密度。

目的

我们的研究旨在评估不同解剖学诊断的先天性紫绀型心脏病儿童的骨矿物质密度。

设计/方法:本研究为横断面、观察性研究,纳入了在曼苏拉大学儿童医院心内科就诊的 39 名(男 20 名)不同解剖学诊断的先天性紫绀型心脏病患者。所有患者均接受了人体测量、血氧饱和度评估和腰椎骨矿物质密度的双能 X 线吸收法检测。

结果

39 名纳入患者中,有 6 名(15.4%)患者存在骨矿物质密度降低,13 名(33.3%)患者的骨矿物质密度 Z 值在-1 到-2 之间,而 20 名(51.3%)患者的骨矿物质密度 Z 值大于-1。

结论

紫绀型先天性心脏病患儿可出现低骨矿物质密度,因此需要考虑评估骨矿物质密度,如果需要还需要进行早期治疗,以避免进一步的并发症。

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