Colozza M, Grignani F, Crino L, Tonato M, Davis S
Istituto di Clinica Medica, Università di Perugia, Italy.
Anticancer Res. 1988 May-Jun;8(3):457-8.
A patient with biopsy-proven spindle cell carcinoma, of unknown primary site, metastatic to the neck and to the lung, was treated with chemotherapy consisting of cisplatin (20 mg/m2/day) on days 1-5 and 5-fluorouracil (1000 mg/m2/day) on days 1-5. The regimen was repeated every 28 days. The patient had a complete response confirmed by computerized tomography. The patient is in a disease-free status 12 months after diagnosis. Toxicity was mild. To our knowledge, this case represents the first chemotherapy induced complete response documented in this rare entity.
一名经活检证实为梭形细胞癌的患者，原发部位不明，已转移至颈部和肺部，接受了化疗，化疗方案为第1 - 5天使用顺铂（20 mg/m²/天），第1 - 5天使用5-氟尿嘧啶（1000 mg/m²/天）。该方案每28天重复一次。经计算机断层扫描确认患者获得完全缓解。患者在诊断后12个月处于无病状态。毒性反应轻微。据我们所知，该病例是这种罕见疾病中首例有记录的化疗诱导完全缓解病例。
