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一例因脑脊液漏导致的吸入性肺炎,该脑脊液漏与内镜鼻窦手术期间医源性颅底损伤的延迟识别相关。

A Case of Aspiration Pneumonia Caused by Cerebrospinal Fluid Leaks Associated with Delayed Identification of Iatrogenic Skull Base Injury during Endoscopic Sinus Surgery.

作者信息

Anzai Takashi, Baba Akira, Ito Shin, Suzuki Yo, Tajima Shori, Hara Satoshi, Takata Yusuke, Matsumoto Fumihiko, Ikeda Katsuhisa

机构信息

Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.

Department of Radiology, The Jikei University School of Medicine, Tokyo, Japan.

出版信息

Case Rep Otolaryngol. 2021 Apr 8;2021:5532194. doi: 10.1155/2021/5532194. eCollection 2021.

Abstract

Cerebrospinal fluid (CSF) leaks associated with endoscopic sinus surgery (ESS) are a rare complication affecting approximately 0.09% of patients. Although meningitis is a well-known complication of CSF leaks, the case we present is a rare and cautionary case of CSF leakage associated with ESS leading to aspiration pneumonia. A 43-year-old man with CSF leaks after ESS was referred to our hospital. After the operation, sometimes, he reported having a serous nasal discharge from the right side when he bent over, and he woke up choking on something every day. He also experienced headache, fever, fatigue, and cough. Interestingly, chest computed tomography (CT) showed a consolidation and ground-glass opacity in the posterior segments of the right upper lobes and superior segments of the bilateral lower lobes. These CT imaging findings were similar to those of aspiration pneumonia in bedridden patients who are always in a supine position. These findings suggest that CSF caused aspiration pneumonia. To the best of our knowledge, no case of aspiration pneumonia caused by CSF during endoscopic sinus surgery has been reported until now. If a patient with CSF leakage after ESS experiences fever, cough, or fatigue, physicians should consider aspiration pneumonia in addition to meningitis.

摘要

与鼻内镜鼻窦手术(ESS)相关的脑脊液(CSF)漏是一种罕见的并发症,约0.09%的患者会受到影响。虽然脑膜炎是脑脊液漏的一种众所周知的并发症,但我们所呈现的病例是一例罕见的、警示性的与ESS相关的脑脊液漏导致吸入性肺炎的病例。一名ESS术后出现脑脊液漏的43岁男性被转诊至我院。术后,他有时报告弯腰时右侧有浆液性鼻分泌物,并且每天醒来时都会被某物呛到。他还经历了头痛、发热、疲劳和咳嗽。有趣的是,胸部计算机断层扫描(CT)显示右上叶后段和双侧下叶上段有实变和磨玻璃影。这些CT影像学表现与长期仰卧位的卧床患者的吸入性肺炎相似。这些发现提示脑脊液导致了吸入性肺炎。据我们所知,迄今为止尚未有内镜鼻窦手术期间脑脊液导致吸入性肺炎的病例报告。如果ESS术后脑脊液漏的患者出现发热、咳嗽或疲劳,医生除了考虑脑膜炎外,还应考虑吸入性肺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/8052149/3e62b5fb2723/CRIOT2021-5532194.001.jpg

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本文引用的文献

1
Chronic Aspiration Pneumonitis Caused by Spontaneous Cerebrospinal Fluid Fistulae of the Skull Base.
Laryngoscope. 2021 Mar;131(3):462-466. doi: 10.1002/lary.28757. Epub 2020 May 25.
2
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N Engl J Med. 2019 Feb 14;380(7):651-663. doi: 10.1056/NEJMra1714562.
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