Paul Mary E, Castillo Marné, Emmanuel Patricia, Bauermeister Jose A, Mena Leandro A, Sullivan Patrick S, Hightow-Weidman Lisa B
Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA.
Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Mhealth. 2021 Apr 20;7:38. doi: 10.21037/mhealth-20-65. eCollection 2021.
A number of mobile health (mHealth) interventions have been shown to be effective and highly acceptable tools for improving human immunodeficiency virus (HIV) prevention and care for youth. Scale-up of efficacious technology-based interventions is challenging and best practices for scale-up have not been clearly established. Developers of mHealth interventions should have plans in mind for wide scale implementation throughout all stages of development including planning, during trials and during analysis and dissemination. We discuss an approach of focus on researchers, funders and potential implementers including members of the community, public health practitioners and policymakers during initial planning, trials, analysis and dissemination, and planning for scale-up. Development of the P3 (Prepared, Protected, emPowered) mobile application (app), an intervention built to encourage and increase pre-exposure prophylaxis (PrEP) adherence among young men who have sex with men (YMSM) and young transgender women who have sex with men (YTWSM), is discussed in terms of designing for scale-up and lessons learned.
一些移动健康（mHealth）干预措施已被证明是改善青少年艾滋病毒预防和护理的有效且高度可接受的工具。扩大基于有效技术的干预措施具有挑战性，且扩大规模的最佳实践尚未明确确立。mHealth干预措施的开发者在整个开发阶段，包括规划、试验期间以及分析和传播阶段，都应考虑大规模实施的计划。我们讨论一种方法，即在初始规划、试验、分析和传播以及扩大规模规划期间，关注研究人员、资助者和潜在实施者，包括社区成员、公共卫生从业者和政策制定者。本文将以P3（准备好、受保护、有力量）移动应用程序（app）为例，讨论其在设计扩大规模方面的经验教训。该应用程序旨在鼓励并提高男男性行为青年（YMSM）和与男性发生性行为的年轻跨性别女性（YTWSM）的暴露前预防（PrEP）依从性。
