伊维菌素与新冠病毒：让我们秉持“同一健康”视角。
Ivermectin & COVID-19: Let's keep a One Health perspective.
作者信息
Domingo-Echaburu Saioa, Orive Gorka, Lertxundi Unax
机构信息
Pharmacy Service. Alto Deba-Integrated Health Care Organization, Arrasate, Gipuzkoa, Spain.
NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country UPV/EHU, Paseo de La Universidad 7, Vitoria-Gasteiz, 01006, Spain.
出版信息
Sustain Chem Pharm. 2021 Jun;21:100438. doi: 10.1016/j.scp.2021.100438. Epub 2021 Apr 18.
Despite uncertainty about its clinical benefit, ivermectin has been used for COVID 19, even in prophylaxis. The European Medicines Agency (EMA) has advised against its use for the prevention or treatment of COVID-19 outside randomised clinical trials. Although the potential negative environmental effects of ivermectin have been widely recognised when used in veterinary medicine, scarce attention has been devoted to the potential ecotoxicological impact of human use. We believe is time to include One Health's philosophy in our daily practice. In the specific case of ivermectin & COVID 19, environmental aspects should also be on the table.
尽管伊维菌素的临床益处存在不确定性，但它已被用于治疗新冠肺炎，甚至用于预防。欧洲药品管理局（EMA）已建议，在随机临床试验之外，不要将其用于预防或治疗新冠肺炎。虽然伊维菌素在兽医学中使用时，其潜在的负面环境影响已得到广泛认可，但人们很少关注其在人类使用中可能产生的生态毒理学影响。我们认为，是时候将“同一健康”理念纳入我们的日常实践了。就伊维菌素和新冠肺炎这一具体情况而言，环境方面的问题也应予以考虑。
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