Liu Xiaoyi, Liu Hui, Lan Qing, Zheng Xiangde, Duan Jun, Zeng Fanwei
Department of Critical Care Medicine, The Central Hospital of Dazhou, Dazhou, Sichuan, PR China.
Ophthalmology, The Central Hospital of Dazhou, Dazhou, Sichuan, PR China.
Med Clin (Engl Ed). 2021 Apr 23;156(8):386-389. doi: 10.1016/j.medcle.2020.11.016. Epub 2021 Apr 17.
In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance.
This was a retrospective observational study. We defined the early PP group as mild COVID-19 patients who were placed into a prone position within 24 h of admission; others served as the control group. We recorded basic data and outcomes of early PP and compared the results to those of controls.
After 1 day of treatment, oxygenation was greater in the early PP group than in the control group (P/F: 421.6 ± 39.74 vs. 382.1 ± 38.84 mmHg [1 mmHg = 0.133 kPa], < 0.01). And early PP group spent less total time in prone position (11.1 ± 4.17 vs. 16.9 ± 5.20 days, < 0.01), and required shorter hospitalization duration (12.2 ± 4.49 vs. 23.2 ± 4.83 days, < 0.001).
Early PP treatment can improve hypoxia and shorten the prone position time and hospitalization duration in mild COVID-19 patients. It is a potential clinically applicable intervention.
2019年12月，中国武汉暴发了2019冠状病毒病（COVID-19）。我院收治的部分患者接受了早期俯卧位通气（PP）治疗。在此，我们分析了其临床意义。
这是一项回顾性观察研究。我们将早期PP组定义为入院24小时内接受俯卧位通气的轻症COVID-19患者；其他患者作为对照组。我们记录了早期PP组的基本数据和治疗结果，并与对照组进行比较。
治疗1天后，早期PP组的氧合情况优于对照组（P/F：421.6±39.74 vs. 382.1±38.84 mmHg [1 mmHg = 0.133 kPa]，P<0.01）。早期PP组的总俯卧位时间较短（11.1±4.17天 vs. 16.9±5.20天，P<0.01），住院时间也较短（12.2±4.49天 vs. 23.2±4.83天，P<0.001）。
早期PP治疗可改善轻症COVID-19患者的缺氧状况，缩短俯卧位时间和住院时间。这是一种具有潜在临床应用价值的干预措施。
