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开放经椎间孔腰椎椎体间融合术的围手术期改良与微创经椎间孔腰椎椎体间融合术的短期疗效相当。

Perioperative Modifications to the Open TLIF Provide Comparable Short-term Outcomes to the MIS-TLIF.

作者信息

Berkman Richard A, Wright Amanda H, Khan Inamullah, Sivaganesan Ahilan

机构信息

Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN.

出版信息

Clin Spine Surg. 2022 Feb 1;35(1):E202-E210. doi: 10.1097/BSD.0000000000001181.

Abstract

STUDY DESIGN

This study is a retrospective review of patients' charts and data from longitudinally collected clinical outcomes and opioid use.

OBJECTIVE

In the current study, we aim to compare short-term outcomes data for 139 Open transforaminal interbody fusion (TLIF) patients to recently published data for tubular and endoscopic MIS-TLIF.

BACKGROUND CONTEXT

In response to the downsides associated with Open TLIF, such as large incision, blood loss, delayed ambulation, prolonged hospitalization, and opioid-reliance, spine surgeons developed tubular retractor based "minimally-invasive" TLIF. However, the traditional Open TLIF retains its significance in terms of providing successful fusion and improved patient-reported outcomes (PROs).

METHODS

We adapted several techniques with an aim to improve short-term outcomes for our Open TLIF patients that combined extensive perioperative counselling, an emphasis on early mobilization, avoidance of overuse of opioid analgesics, early discharge with home care arrangements, use of a posthospitalization drainage tube with intraoperative surgical modifications using small incisions (4-5 cm), a narrow 20 mm retractor, minimal muscle injury, and use of a cell saver to minimize net blood loss. The demographics and perioperative results were compared with data from recent MIS-TLIF studies using Student t test for continuous and χ2/exact test for categorical variables.

RESULTS

Among the total 139 patients, 115 underwent a single-level procedure, 90% of whom were discharged on the first postoperative day (length of stay=1.13±0.47 d) with an average net estimated blood loss of 176.17±87.88 mL. There were 24 two-level procedures with an average length of stay of 1.57±0.84 days, average net estimated blood loss was 216.96±85.70 mL. The patients had statistically significant improvements in PROs at 3 and 12 months.

CONCLUSIONS

The results of this study identify that patients who underwent modified Open TLIF demonstrated favorable short-term outcomes, as compared with the tubular MIS-TLIF, by virtue of avoidance of blood transfusions, shorter hospital stays, and significantly less opioid usage while experiencing satisfactory PROs.

摘要

研究设计

本研究是对患者病历以及纵向收集的临床结局和阿片类药物使用数据的回顾性分析。

目的

在本研究中,我们旨在将139例开放式经椎间孔腰椎椎体间融合术(TLIF)患者的短期结局数据与最近发表的管状及内镜下微创TLIF数据进行比较。

背景

针对开放式TLIF的缺点,如切口大、失血多、活动延迟、住院时间延长和阿片类药物依赖等,脊柱外科医生开发了基于管状牵开器的“微创”TLIF。然而,传统的开放式TLIF在实现成功融合和改善患者报告结局(PROs)方面仍具有重要意义。

方法

我们采用了多种技术,旨在改善开放式TLIF患者的短期结局,包括广泛的围手术期咨询、强调早期活动、避免过度使用阿片类镇痛药、通过家庭护理安排实现早期出院、使用术后引流管并在术中采用小切口(4 - 5厘米)进行手术改良、使用20毫米窄牵开器、尽量减少肌肉损伤以及使用血液回收机以尽量减少净失血量。使用Student t检验对连续变量以及χ2/确切概率法对分类变量,将人口统计学和围手术期结果与最近微创TLIF研究的数据进行比较。

结果

在总共139例患者中,115例行单节段手术,其中90%在术后第一天出院(住院时间 = 1.13±0.47天),平均估计净失血量为176.17±87.88毫升。24例行双节段手术,平均住院时间为1.57±0.84天,平均估计净失血量为216.96±85.70毫升。患者在3个月和12个月时的PROs有统计学上的显著改善。

结论

本研究结果表明,与管状微创TLIF相比,接受改良开放式TLIF的患者在避免输血、缩短住院时间以及显著减少阿片类药物使用量的同时,获得了令人满意的PROs,从而展现出良好的短期结局。

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