Salesi Hospital, Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona Umberto I G M Lancisi G Salesi, Department of Women's and Children's Health, via Corridoni, 11, 60123 Ancona, Italy.
Salesi Hospital, Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona Umberto I G M Lancisi G Salesi, Department of Women's and Children's Health, via Corridoni, 11, 60123 Ancona, Italy.
Diabetes Res Clin Pract. 2021 May;175:108838. doi: 10.1016/j.diabres.2021.108838. Epub 2021 Apr 24.
To determine if diabetes awareness campaigns are an effective intervention to reduce diabetes ketoacidosis at diagnosis of type 1 diabetes in children and youth.
Search strategies included PubMed, Scopus, CINAHL and WOS electronic databases, hand search of select journals and a grey literature search "Google" search to include all relevant information. Studies included community-based interventions focused on children younger than 18 years old. The difference in the frequency of DKA was measured in two separate comparisons; before and after perform awareness campaigns in the same area, and between areas with and without intervention campaigns.
Of 1136 records identified, 14 studies were eligible for the analysis. The first group of 12 studies measured DKA at diagnosis, before (n = 6548 individuals) and after (n = 4931 individuals) the awareness campaigns. The pooled difference was a reduction of 7.20% (95%CI: 0.99-13.41). The second group of four studies measured the difference in an area with no intervention (n = 338 individuals) and in an area with an awareness campaign (n = 187 individuals). The pooled difference in DKA was 35.71% (95%CI: 5.81-65.61).
This review demonstrated that DKA awareness campaigns are effective to reduce DKA among children and adolescents with type 1 diabetes and the core components that explain why these campaigns are effective. Back to top.
确定糖尿病意识宣传活动是否是一种有效的干预措施，可降低儿童和青少年 1 型糖尿病诊断时的糖尿病酮症酸中毒（DKA）发生率。
检索策略包括 PubMed、Scopus、CINAHL 和 WOS 电子数据库、选择性期刊的手工检索以及“Google”搜索的灰色文献检索，以纳入所有相关信息。研究包括以 18 岁以下儿童为重点的基于社区的干预措施。通过两种独立比较来衡量 DKA 的发生率差异：在同一地区开展意识宣传活动前后，以及在有和无干预活动的地区之间。
在确定的 1136 条记录中，有 14 项研究符合分析条件。第一组 12 项研究在诊断时测量 DKA，在意识宣传活动之前（n=6548 人）和之后（n=4931 人）进行。汇总差异为减少 7.20%（95%CI：0.99-13.41）。第二组四项研究测量无干预区（n=338 人）和有宣传活动区（n=187 人）的 DKA 差异。DKA 的汇总差异为 35.71%（95%CI：5.81-65.61）。
本综述表明，DKA 意识宣传活动可有效降低 1 型糖尿病儿童和青少年的 DKA 发生率，并解释了这些活动为何有效的核心组成部分。
