Otorhinolaryngology Unit, IRCCS Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Facial Plast Surg. 2021 Oct;37(5):681-687. doi: 10.1055/s-0041-1726445. Epub 2021 Apr 26.
The aim of the present study is to report our preliminary experience with the vastus lateralis myofascial free flap (VLMFF) for tongue reconstruction according to tongue and donor site functional outcomes. Twelve consecutive patients (F: 5; median age: 54.0 years, interquartile range or IQR 42.75-69.0) were included. The validated European Organization for Research and Treatment of Cancer of the Head and Neck 35 Quality of Life Questionnaire (EORTC QLQ-H&N35) and the performance status scale for head and neck cancer (PSS-HN) questionnaires were used to assess the health-related quality of life (HRQOL). The lower extremity functional scale (LEFS) was used to self-report the donor area function. All patients were successfully treated, and no VLMFF failure was detected during a median follow-up period of 10.5 months (IQR: 6.5-33.0). The HRQOL showed a median EORTC QLQ-H&N35 score of 56.0 (IQR: 50.0-72.5). The median PSS-HN score was 80.0 (IQR: 45.0-95.0), 75.0 (IQR: 62.5-100.0), 75.0 (IQR: 62.5-100.0) for "Normalcy of Diet," "Public Eating," and "Understandability of Speech," respectively. The self-reported function of the lower extremities (donor area) showed a median LEFS of 59.0 (IQR: 32.5-74.0). This study reports optimistic data regarding the functional and quality of life outcomes after tongue reconstruction using VLMFF. Prospective controlled studies are needed to demonstrate advantages and disadvantages when compared with other reconstructive techniques.
本研究旨在报告根据舌部和供区功能结果，应用股外侧肌筋膜游离皮瓣（VLMFF）进行舌再造的初步经验。共纳入 12 例连续患者（女性 5 例；中位年龄 54.0 岁，四分位距或 IQR 42.75-69.0）。采用欧洲癌症研究与治疗组织头颈部 35 项生活质量问卷（EORTC QLQ-H&N35）和头颈部癌症体力状况量表（PSS-HN）评估健康相关生活质量（HRQOL）。下肢功能量表（LEFS）用于自我报告供区功能。所有患者均成功治疗，中位随访 10.5 个月（IQR：6.5-33.0）期间未发现 VLMFF 失败。HRQOL 显示 EORTC QLQ-H&N35 中位评分为 56.0（IQR：50.0-72.5）。PSS-HN 中位评分为 80.0（IQR：45.0-95.0）、75.0（IQR：62.5-100.0）和 75.0（IQR：62.5-100.0），分别为“饮食正常”、“公共进食”和“言语理解”。下肢（供区）的自我报告功能显示 LEFS 中位评分为 59.0（IQR：32.5-74.0）。本研究报告了应用 VLMFF 进行舌再造后功能和生活质量结果的乐观数据。需要前瞻性对照研究来比较与其他重建技术的优缺点。
