[肝硬化患者肌肉减少症的评估与干预策略]
[Assessment and intervention strategies for sarcopenia in patients with liver cirrhosis].
作者信息
Xiao H J, Han T
机构信息
The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China Department of Nutrition, The Third Central Hospital of Tianjin, Tianjin 300170, China Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin 300170, China Artificial Cell Engineering Technology Research Center, Tianjin 300170, China Tianjin Institute of Hepatobiliary Disease, Tianjin 300170, China.
The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China Department of Gastroenterology and Hepatology, The Third Central Hospital of Tianjin, Tianjin 300170, China Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin 300170, China Artificial Cell Engineering Technology Research Center, Tianjin 300170, China Tianjin Institute of Hepatobiliary Disease, Tianjin 300170, China.
出版信息
Zhonghua Gan Zang Bing Za Zhi. 2021 Mar 20;29(3):199-203. doi: 10.3760/cma.j.cn501113-20210113-00025.
Sarcopenia is a common complication in patients with liver cirrhosis, which has an adverse effect on the clinical outcome and prognosis. Attention must be paid to early detection and active diagnosis and treatment. Clinically, the diagnosis process of finding suspicious cases can be traced through screening-assessment-diagnosis-severity evaluation. On the ground of treating liver cirrhosis and its complications, reasonable nutritional intervention and exercise are currently important measures for the treatment of liver cirrhosis with sarcopenia, and the role of hormone supplementation and drug therapy for skeletal muscle metabolism needs to be further investigated.
肌肉减少症是肝硬化患者的常见并发症，对临床结局和预后有不利影响。必须重视早期发现并积极进行诊断和治疗。临床上，发现可疑病例的诊断过程可通过筛查-评估-诊断-严重程度评估来追溯。在治疗肝硬化及其并发症的基础上，合理的营养干预和运动是目前治疗肝硬化合并肌肉减少症的重要措施，激素补充和药物治疗对骨骼肌代谢的作用尚需进一步研究。
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