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为什么女性仍死于产科出血?高、低资源环境观点的叙述性综述。

Why are women still dying from obstetric hemorrhage? A narrative review of perspectives from high and low resource settings.

机构信息

Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

出版信息

Int J Obstet Anesth. 2021 May;46:102982. doi: 10.1016/j.ijoa.2021.102982. Epub 2021 Mar 25.

DOI:10.1016/j.ijoa.2021.102982
PMID:33903002
Abstract

The possibility of hemorrhage will always co-exist with pregnancy, whether anticipated or not. It remains the unwelcome guest in the corner of every delivery room, stealing the lives of young women every day across the globe. In 2014, the World Health Organization reported that hemorrhage was the leading contributor to maternal mortality worldwide, with nearly 75% of maternal deaths due to postpartum hemorrhage. In low resource settings, while maternal mortality is decreasing, hemorrhage remains the single most important contributor to maternal death. Hospital-based deliveries with skilled birth attendants have been encouraged to improve outcomes and, as a result, hospital births have dramatically increased. However, access to higher levels of emergency obstetric care as well as blood products and therapeutic resources remain limiting factors. Meanwhile, in high resource settings, maternal mortality from hemorrhage is increasing, particularly among women of color. While very rare, mortality from hemorrhage generally follows medical interventions such as surgical management of placenta accreta or emergency cesarean section. Primary prevention therefore requires careful selection and conduct of medical interventions, as well as the provision of high quality, supportive, and safe maternity care. It is clear that there is not one single solution in preventing obstetric hemorrhage on a global scale. The international community must employ creative solutions to reduce this ever-present problem.

摘要

妊娠总是伴随着出血的可能性,无论是预期内的还是意外的。它一直是每个产房角落里不受欢迎的客人,每天在全球夺走年轻女性的生命。2014 年,世界卫生组织报告称,出血是全球孕产妇死亡的主要原因,近 75%的孕产妇死亡是由于产后出血。在资源匮乏的环境中,尽管孕产妇死亡率在下降,但出血仍然是孕产妇死亡的最重要原因。鼓励有熟练接生员的医院分娩,以改善结果,因此,医院分娩率显著增加。然而,获得更高水平的紧急产科护理以及血液制品和治疗资源仍然是限制因素。与此同时,在资源丰富的环境中,出血导致的孕产妇死亡率正在上升,尤其是有色人种的女性。虽然非常罕见,但出血导致的死亡率通常是在进行胎盘植入的手术管理或紧急剖宫产等医疗干预之后。因此,初级预防需要仔细选择和进行医疗干预,并提供高质量、支持性和安全的产妇护理。显然,在全球范围内防止产科出血没有一个单一的解决方案。国际社会必须采用创造性的解决方案来减少这一始终存在的问题。

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