Richards M A, Webb J A, Jewell S E, Amess J A, Wrigley P F, Lister T A
ICRF Department of Medical Oncology, St Bartholomew's Hospital, London, UK.
Br J Cancer. 1988 Apr;57(4):412-5. doi: 10.1038/bjc.1988.93.
Detection of bone marrow infiltration by lymphoma with low field strength magnetic resonance imaging (MRI) has been assessed. Measurements of spin lattice relaxation time (T1) were made in 31 patients with lymphoma and compared with the results of bone marrow biopsy and with T1 measurements made on 90 healthy volunteers. The sensitivity of MRI was excellent in patients for whom the microscopic pattern of marrow infiltration was diffuse, but poor in those with microscopically focal infiltration.
利用低场强磁共振成像(MRI)检测淋巴瘤骨髓浸润情况已得到评估。对31例淋巴瘤患者进行了自旋晶格弛豫时间(T1)测量,并将结果与骨髓活检结果以及90名健康志愿者的T1测量结果进行比较。对于骨髓浸润微观模式为弥漫性的患者,MRI的敏感性极佳,但对于微观上呈局灶性浸润的患者,敏感性较差。