Central Laboratory of Shanghai Fengxian District Central Hospital, Shanghai 201499, China.
Department of Radiation Oncology, Ren Ji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Sheng Li Xue Bao. 2021 Apr 25;73(2):175-180.
The great omentum is an intraperitoneal organ and plays an important role in protecting the environment of the peritoneal cavity. Several specialized innate immune cells including B1 cells and resident macrophages are found in the omentum, which may be attributed to the unique niche and its special stromal cells. However, it is not clear how these omental innate immune cells contribute to the peritoneal immunity. This review attempts to summarize the latest research on the omental innate immunity and discuss its involvement in the immune response of the peritoneal cavity.
大网膜是一种腹腔内器官,在保护腹腔内环境方面起着重要作用。大网膜中存在几种专门的固有免疫细胞,包括 B1 细胞和固有巨噬细胞,这可能归因于其独特的生态位及其特殊的基质细胞。然而,目前尚不清楚这些大网膜固有免疫细胞如何促进腹膜免疫。本文试图总结大网膜固有免疫的最新研究进展,并探讨其在腹腔免疫反应中的作用。