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一例中枢神经系统放线菌病:极为罕见!

A Case of CNS Actinomycosis: Rarer than Rare!

作者信息

Limaye Harshad S, A Hinduja Anupa R, Verma Mitusha, Oak Pradyumna J

机构信息

Department of General Medicine, Nanavati Superspeciality Hospital, Mumbai, Maharashtra, India.

Neurosciences (Neurology and Neurosurgery), Nanavati Superspeciality Hospital, Mumbai, Maharashtra, India.

出版信息

Neurol India. 2021 Mar-Apr;69(2):475-477. doi: 10.4103/0028-3886.314572.

Abstract

We report a case of cerebral actinomycosis in a 62-year-old male who presented with right-sided weakness and focal convulsions. MRI scan showed a solid intra axial space occupying lesion in the left frontal lobe. Left parietal craniotomy with intra-operative USG guided aspiration and excision of the mass (containing necrotic material) was done. Actinomyces israelii was isolated from the aspirated material. Patient received ceftriaxone and clindamycin for 12 weeks. Physiotherapy and anti-epileptic drugs were continued. On subsequent follow-up visits, his power improved to 5/5 in lower limb, 4/5 in proximal upper limb, 2/5 in distal upper limb. Actinomycosis can cause diverse clinical manifestations, and therefore clinical suspicion is key to diagnosis. Early diagnosis and treatment can lead to good treatment outcomes.

摘要

我们报告一例62岁男性脑放线菌病病例,该患者表现为右侧肢体无力和局灶性抽搐。MRI扫描显示左额叶有一个实性轴内占位性病变。进行了左顶骨开颅手术,术中在超声引导下对肿块(含有坏死物质)进行抽吸和切除。从抽吸物中分离出以色列放线菌。患者接受了12周的头孢曲松和克林霉素治疗。继续进行物理治疗和抗癫痫药物治疗。在随后的随访中,他下肢肌力恢复到5/5,近端上肢肌力为4/5,远端上肢肌力为2/5。放线菌病可导致多种临床表现,因此临床怀疑是诊断的关键。早期诊断和治疗可带来良好的治疗效果。

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