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肌阵挛的一个不寻常病例:其 LGI1 抗体

An Unusual Case of Muscle Twitching: Its LGI1.

机构信息

Department of Neurology, Sir Ganga Ram Hospital, Old Rajendra Nagar, New Delhi, India.

出版信息

Neurol India. 2021 Mar-Apr;69(2):493-494. doi: 10.4103/0028-3886.314549.

DOI:10.4103/0028-3886.314549
PMID:33904485
Abstract

A 50-year-old male, presented with a two-months history of ascending paresthesias, with continuous twitchings over the body, associated with insomnia. His electromyography (EMG) revealed neuromyotonia and was diagnosed as a case of peripheral nerve hyperexcitability (PNH) syndrome due to Leucin-rich glioma-inactivated 1 (LGI1) antibody. He showed significant improvement with intravenous immunoglobulin and carbamazepine.

摘要

一位 50 岁男性,表现为两个月的上升性感觉异常,伴有全身持续性抽搐,伴有失眠。他的肌电图(EMG)显示神经肌强直,被诊断为由于亮氨酸丰富胶质瘤失活 1(LGI1)抗体引起的周围神经兴奋性过高(PNH)综合征。他接受静脉注射免疫球蛋白和卡马西平治疗后有显著改善。

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