Research Center for Evidence-Based Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran AND Department of Ophthalmology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Research Center for Evidence-Based Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.
Iran J Allergy Asthma Immunol. 2021 Apr 17;20(2):140-146.
The coronavirus disease 2019 (COVID-19) pandemic in Iran is part of the worldwide pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The present study aimed to demonstrate the clinical characteristics of patients affected by COVID-19, in our tertiary teaching hospital. Medical records and compiled data of 668 patients with suspected COVID-19 were obtained retrospectively between January to April 2020. The present study outcomes included demographic features of infected patients, underlying diseases and conditions, the relationship between the results of reverse transcription-polymerase chain reaction (RT-PCR) or CT-scan with the manifestations of the disease, mortality rate, and age distribution of fatalities among men and women. The median age of hospitalized patients was 63 years old (from 18 to 94). The patients' chief complaints in the admission time were cough, dyspnea, fever, and gastrointestinal problems, respectively. Hospitalized patients' common comorbidities were hypertension (HTN), and cardiovascular disease (CVD) (24%), diabetes mellitus (DM) (21.5%), asthma, or chronic obstructive pulmonary disease (COPD) (6%), or other underlying diseases (15.5%). One-third of patients had no comorbidity according to the data of medical records. In hospitalized patients, 169 (84.5%) had positive RT-PCR, and 156 (78%) had positive chest CT findings. The mortality rate of males was higher than females (66.3% vs. 33.3%) and in patients with positive RT-PCR compared to patients with positive chest CT-scan findings. The majority of deaths had a history of DM or HTN/CVD in their medical records. The chief complaint of patients was cough. DM and HTN or CVD were the common underlying disease related to death in hospitalized cases. Besides, the hospitalization and mortality rate in males was higher than in females. About 87% of dead hospitalized cases had positive RT-PCR results, and this rate was 82% for chest CT results.
2019 年冠状病毒病（COVID-19）疫情是由严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）引起的全球大流行的一部分。本研究旨在展示我们三级教学医院中受 COVID-19 影响的患者的临床特征。我们回顾性地获得了 2020 年 1 月至 4 月间 668 例疑似 COVID-19 患者的病历和汇总数据。本研究的结果包括感染患者的人口统计学特征、基础疾病和条件、逆转录-聚合酶链反应（RT-PCR）或 CT 扫描结果与疾病表现之间的关系、死亡率以及男女死亡者的年龄分布。住院患者的中位年龄为 63 岁（18-94 岁）。住院时患者的主要症状为咳嗽、呼吸困难、发热和胃肠道问题。住院患者的常见合并症为高血压（HTN）和心血管疾病（CVD）（24%）、糖尿病（DM）（21.5%）、哮喘或慢性阻塞性肺疾病（COPD）（6%）或其他基础疾病（15.5%）。根据病历数据，三分之一的患者没有合并症。在住院患者中，169 例（84.5%）RT-PCR 检测阳性，156 例（78%）胸部 CT 检查阳性。男性的死亡率高于女性（66.3%比 33.3%），且 RT-PCR 阳性患者的死亡率高于胸部 CT 扫描阳性患者。大多数死亡病例的病历中都有 DM 或 HTN/CVD 的病史。患者的主要症状是咳嗽。DM 和 HTN/CVD 是住院患者死亡相关的常见基础疾病。此外，男性的住院率和死亡率均高于女性。约 87%的死亡住院病例 RT-PCR 结果为阳性，胸部 CT 结果为阳性的比例为 82%。
