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本文引用的文献

1
Current reporting of usability and impact of mHealth interventions for substance use disorder: A systematic review.当前关于移动健康干预物质使用障碍的可用性和影响的报告:系统评价。
Drug Alcohol Depend. 2020 Oct 1;215:108201. doi: 10.1016/j.drugalcdep.2020.108201. Epub 2020 Aug 2.
2
Is craving a risk factor for substance use among treatment-seeking individuals with alcohol and other drugs use disorders? A meta-analytic review.寻求治疗的酒精和其他药物使用障碍患者中,渴望是物质使用的风险因素吗?一项荟萃分析综述。
Drug Alcohol Depend. 2020 Jul 1;212:108002. doi: 10.1016/j.drugalcdep.2020.108002. Epub 2020 Apr 26.
3
Self-Esteem and Non-Medical Use of Prescription Drugs among College Students: Coping as a Mediator.大学生自尊与处方药物的非医疗使用:应对作为中介。
Subst Use Misuse. 2020;55(8):1309-1319. doi: 10.1080/10826084.2020.1735441. Epub 2020 Mar 23.
4
The relationship between perceived stress and depression in substance use disorder treatment.物质使用障碍治疗中感知压力与抑郁的关系。
Drug Alcohol Depend. 2020 Feb 1;207:107819. doi: 10.1016/j.drugalcdep.2019.107819. Epub 2019 Dec 23.
5
Sex differences in stress-related alcohol use.压力相关饮酒行为中的性别差异。
Neurobiol Stress. 2019 Feb 8;10:100149. doi: 10.1016/j.ynstr.2019.100149. eCollection 2019 Feb.
6
Stress and substance use among sexual and gender minority individuals across the lifespan.不同年龄段性少数和性别少数群体中的压力与物质使用情况
Neurobiol Stress. 2018 Dec 27;10:100146. doi: 10.1016/j.ynstr.2018.100146. eCollection 2019 Feb.
7
The use of crowdsourcing in addiction science research: Amazon Mechanical Turk.众包在成瘾科学研究中的应用:亚马逊土耳其机器人。
Exp Clin Psychopharmacol. 2019 Feb;27(1):1-18. doi: 10.1037/pha0000235. Epub 2018 Nov 29.
8
Randomized controlled trial of a positive affect intervention for methamphetamine users.一项针对冰毒使用者的积极情绪干预的随机对照试验。
Drug Alcohol Depend. 2018 Nov 1;192:8-15. doi: 10.1016/j.drugalcdep.2018.07.029. Epub 2018 Sep 5.
9
Prescription tranquilizer/sedative misuse prevalence and correlates across age cohorts in the US.美国各年龄队列中处方镇静剂/安定类药物滥用的流行情况及其相关因素。
Addict Behav. 2018 Dec;87:24-32. doi: 10.1016/j.addbeh.2018.06.013. Epub 2018 Jun 12.
10
Depressive symptoms and problematic alcohol and other substance use in 1476 gay, bisexual, and other MSM at three research sites in Kenya.在肯尼亚的三个研究点,1476 名男同性恋、双性恋和其他男男性接触者中,抑郁症状和有问题的酒精及其他物质使用情况。
AIDS. 2018 Jul 17;32(11):1507-1515. doi: 10.1097/QAD.0000000000001847.

美国通过在线众包平台招募的参与者中物质使用的心理社会预测因素和日水平相关因素:每日日记研究。

The Psychosocial Predictors and Day-Level Correlates of Substance Use Among Participants Recruited via an Online Crowdsourcing Platform in the United States: Daily Diary Study.

机构信息

San Francisco Department of Public Health, San Francisco, CA, United States.

Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States.

出版信息

JMIR Public Health Surveill. 2021 Apr 27;7(4):e23872. doi: 10.2196/23872.

DOI:10.2196/23872
PMID:33904828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8114164/
Abstract

BACKGROUND

Alcohol consumption and stimulant use are major public health problems and contribute to morbidity and mortality in the United States. To inform interventions for substance use, there is a need to identify the day-level correlates of substance use by collecting repeated measures data in one's natural environment. There is also a need to use crowdsourcing platforms like Amazon Mechanical Turk (MTurk) to efficiently engage larger populations of people who use alcohol and stimulants in research.

OBJECTIVE

We aimed to (1) utilize daily diaries to examine the temporal relationship between day-level cravings for alcohol and stimulant/substance use (ie, heavy drinking or any drug use) in a given day over 14 days and (2) assess whether depression, negative affect, and self-esteem measured at baseline predict substance use in a given day over 14 days among people who use alcohol and/or stimulants in the United States.

METHODS

Individuals aged ≥18 years in the United States, who reported alcohol or stimulant (ie, cocaine, crack cocaine, and methamphetamine) use in the past year, were recruited using MTurk between March 26 and April 13, 2018. Eligible participants completed a baseline survey and 14 daily surveys online. The baseline survey assessed sociodemographics and psychosocial (ie, depression, affect, self-esteem, and stress) factors. Daily surveys assessed substance use and cravings for alcohol and stimulants. Four multivariable random-intercept logistic regression models were built to examine psychosocial constructs separately along with other significant predictors from bivariate analyses while controlling for age and education.

RESULTS

Among a total of 272 participants, 220 were White, 201 were male, and 134 were men who have sex with men (MSM). The mean age was 36.1 years (SD 10.5). At baseline, 173 participants engaged in any current or past hazardous alcohol consumption, 31 reported using cocaine, 19 reported using methamphetamine, 8 reported using crack cocaine, and 104 reported any noninjection or injection drug use in the past 6 months. Factors independently associated with substance use were depression (adjusted odds ratio [aOR] 1.11, 95% CI 1.02-1.21; P=.01), negative affect (aOR 1.08, 95% CI 1.01-1.16; P=.01), lower levels of self-esteem (aOR 0.90, 95% CI 0.82-0.98; P=.02), and cravings for alcohol (aOR 1.02, 95% CI 1.01-1.03; P<.001) and stimulants (aOR 1.03, 95% CI 1.01-1.04; P=.01). MSM had higher odds of engaging in substance use in all models (model 1: aOR 4.90, 95% CI 1.28-18.70; P=.02; model 2: aOR 5.47, 95% CI 1.43-20.87; P=.01; model 3: aOR 5.99, 95% CI 1.55-23.13; P=.009; and model 4: aOR 4.94, 95% CI 1.29-18.84; P=.01).

CONCLUSIONS

Interventions for substance use should utilize evidenced-based approaches to reduce depression, negative affect, and cravings; increase self-esteem; and engage MSM. Interventions may also consider leveraging technology-based approaches to reduce substance use among populations who use crowdsourcing platforms.

摘要

背景

饮酒和使用兴奋剂是美国的主要公共卫生问题,也是导致发病率和死亡率的原因。为了为物质使用干预措施提供信息,需要通过在自然环境中收集重复测量数据来确定物质使用的日常相关性。还需要使用亚马逊土耳其机器人(MTurk)等众包平台,有效地吸引更多在美国使用酒精和兴奋剂的人群参与研究。

目的

我们旨在(1)利用日常日记,在 14 天内研究每天对酒精和兴奋剂/物质(即重度饮酒或任何药物使用)的渴望与当天物质使用之间的时间关系;(2)评估在基线时测量的抑郁、负性情绪和自尊是否预测在 14 天内,美国使用酒精和/或兴奋剂的人群中每天的物质使用。

方法

2018 年 3 月 26 日至 4 月 13 日期间,我们使用 MTurk 在美国招募年龄≥18 岁、过去一年报告使用酒精或兴奋剂(即可卡因、快克可卡因和甲基苯丙胺)的参与者。合格的参与者在线完成基线调查和 14 天的日常调查。基线调查评估了社会人口统计学和心理社会因素(即抑郁、情绪、自尊和压力)。每日调查评估了物质使用情况以及对酒精和兴奋剂的渴望。在控制年龄和教育程度的情况下,建立了四个多变量随机截距逻辑回归模型,分别研究心理社会结构以及双变量分析中其他显著预测因素。

结果

在总共 272 名参与者中,220 人是白人,201 人是男性,134 人是男男性接触者(MSM)。平均年龄为 36.1 岁(标准差 10.5)。在基线时,173 名参与者有当前或过去的危险饮酒行为,31 名报告使用可卡因,19 名报告使用甲基苯丙胺,8 名报告使用快克可卡因,104 名报告在过去 6 个月内有任何非注射或注射药物使用。与物质使用独立相关的因素包括抑郁(调整后的优势比 [aOR] 1.11,95%置信区间 [CI] 1.02-1.21;P=.01)、负性情绪(aOR 1.08,95% CI 1.01-1.16;P=.01)、较低的自尊水平(aOR 0.90,95% CI 0.82-0.98;P=.02)、对酒精的渴望(aOR 1.02,95% CI 1.01-1.03;P<.001)和兴奋剂(aOR 1.03,95% CI 1.01-1.04;P=.01)。在所有模型中,MSM 参与物质使用的可能性更高(模型 1:aOR 4.90,95% CI 1.28-18.70;P=.02;模型 2:aOR 5.47,95% CI 1.43-20.87;P=.01;模型 3:aOR 5.99,95% CI 1.55-23.13;P=.009;模型 4:aOR 4.94,95% CI 1.29-18.84;P=.01)。

结论

物质使用干预措施应采用循证方法来减少抑郁、负性情绪和渴望;增加自尊;并接触 MSM。干预措施还可以考虑利用基于技术的方法来减少在使用众包平台的人群中的物质使用。