San Francisco Department of Public Health, San Francisco, CA, United States.
Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States.
JMIR Public Health Surveill. 2021 Apr 27;7(4):e23872. doi: 10.2196/23872.
Alcohol consumption and stimulant use are major public health problems and contribute to morbidity and mortality in the United States. To inform interventions for substance use, there is a need to identify the day-level correlates of substance use by collecting repeated measures data in one's natural environment. There is also a need to use crowdsourcing platforms like Amazon Mechanical Turk (MTurk) to efficiently engage larger populations of people who use alcohol and stimulants in research.
We aimed to (1) utilize daily diaries to examine the temporal relationship between day-level cravings for alcohol and stimulant/substance use (ie, heavy drinking or any drug use) in a given day over 14 days and (2) assess whether depression, negative affect, and self-esteem measured at baseline predict substance use in a given day over 14 days among people who use alcohol and/or stimulants in the United States.
Individuals aged ≥18 years in the United States, who reported alcohol or stimulant (ie, cocaine, crack cocaine, and methamphetamine) use in the past year, were recruited using MTurk between March 26 and April 13, 2018. Eligible participants completed a baseline survey and 14 daily surveys online. The baseline survey assessed sociodemographics and psychosocial (ie, depression, affect, self-esteem, and stress) factors. Daily surveys assessed substance use and cravings for alcohol and stimulants. Four multivariable random-intercept logistic regression models were built to examine psychosocial constructs separately along with other significant predictors from bivariate analyses while controlling for age and education.
Among a total of 272 participants, 220 were White, 201 were male, and 134 were men who have sex with men (MSM). The mean age was 36.1 years (SD 10.5). At baseline, 173 participants engaged in any current or past hazardous alcohol consumption, 31 reported using cocaine, 19 reported using methamphetamine, 8 reported using crack cocaine, and 104 reported any noninjection or injection drug use in the past 6 months. Factors independently associated with substance use were depression (adjusted odds ratio [aOR] 1.11, 95% CI 1.02-1.21; P=.01), negative affect (aOR 1.08, 95% CI 1.01-1.16; P=.01), lower levels of self-esteem (aOR 0.90, 95% CI 0.82-0.98; P=.02), and cravings for alcohol (aOR 1.02, 95% CI 1.01-1.03; P<.001) and stimulants (aOR 1.03, 95% CI 1.01-1.04; P=.01). MSM had higher odds of engaging in substance use in all models (model 1: aOR 4.90, 95% CI 1.28-18.70; P=.02; model 2: aOR 5.47, 95% CI 1.43-20.87; P=.01; model 3: aOR 5.99, 95% CI 1.55-23.13; P=.009; and model 4: aOR 4.94, 95% CI 1.29-18.84; P=.01).
Interventions for substance use should utilize evidenced-based approaches to reduce depression, negative affect, and cravings; increase self-esteem; and engage MSM. Interventions may also consider leveraging technology-based approaches to reduce substance use among populations who use crowdsourcing platforms.
饮酒和使用兴奋剂是美国的主要公共卫生问题,也是导致发病率和死亡率的原因。为了为物质使用干预措施提供信息,需要通过在自然环境中收集重复测量数据来确定物质使用的日常相关性。还需要使用亚马逊土耳其机器人(MTurk)等众包平台,有效地吸引更多在美国使用酒精和兴奋剂的人群参与研究。
我们旨在(1)利用日常日记,在 14 天内研究每天对酒精和兴奋剂/物质(即重度饮酒或任何药物使用)的渴望与当天物质使用之间的时间关系;(2)评估在基线时测量的抑郁、负性情绪和自尊是否预测在 14 天内,美国使用酒精和/或兴奋剂的人群中每天的物质使用。
2018 年 3 月 26 日至 4 月 13 日期间,我们使用 MTurk 在美国招募年龄≥18 岁、过去一年报告使用酒精或兴奋剂(即可卡因、快克可卡因和甲基苯丙胺)的参与者。合格的参与者在线完成基线调查和 14 天的日常调查。基线调查评估了社会人口统计学和心理社会因素(即抑郁、情绪、自尊和压力)。每日调查评估了物质使用情况以及对酒精和兴奋剂的渴望。在控制年龄和教育程度的情况下,建立了四个多变量随机截距逻辑回归模型,分别研究心理社会结构以及双变量分析中其他显著预测因素。
在总共 272 名参与者中,220 人是白人,201 人是男性,134 人是男男性接触者(MSM)。平均年龄为 36.1 岁(标准差 10.5)。在基线时,173 名参与者有当前或过去的危险饮酒行为,31 名报告使用可卡因,19 名报告使用甲基苯丙胺,8 名报告使用快克可卡因,104 名报告在过去 6 个月内有任何非注射或注射药物使用。与物质使用独立相关的因素包括抑郁(调整后的优势比 [aOR] 1.11,95%置信区间 [CI] 1.02-1.21;P=.01)、负性情绪(aOR 1.08,95% CI 1.01-1.16;P=.01)、较低的自尊水平(aOR 0.90,95% CI 0.82-0.98;P=.02)、对酒精的渴望(aOR 1.02,95% CI 1.01-1.03;P<.001)和兴奋剂(aOR 1.03,95% CI 1.01-1.04;P=.01)。在所有模型中,MSM 参与物质使用的可能性更高(模型 1:aOR 4.90,95% CI 1.28-18.70;P=.02;模型 2:aOR 5.47,95% CI 1.43-20.87;P=.01;模型 3:aOR 5.99,95% CI 1.55-23.13;P=.009;模型 4:aOR 4.94,95% CI 1.29-18.84;P=.01)。
物质使用干预措施应采用循证方法来减少抑郁、负性情绪和渴望;增加自尊;并接触 MSM。干预措施还可以考虑利用基于技术的方法来减少在使用众包平台的人群中的物质使用。