Hathirat P, Isarangkura P, Panthangkura W, Chuansumrit A, Sasanakul W, Kanasit R
Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Birth Defects Orig Artic Ser. 1988;23(5B):123-7.
The DF given weekly by the RBIT in 14 thalassemia/hemoglobinopathy patients decreased the frequency of URIs and febrile illnesses in 5/10 patients. Five of the six patients had absence of frequent enteritis. There were no instances of pneumonia and otitis media in two patients with frequent infections before DF. Skin color was improved within 3 months. Most of the patients became more active at the same hematocrit level. The height and weight in eight patients was normal. The total number of blood transfusions in all patients was significantly decreased. It is advisable to use weekly DF infusion by RBIT in the patient who cannot afford to use the infusion pump and the full program of iron chelation.
14例地中海贫血/血红蛋白病患者每周接受RBIT给予的去铁胺（DF）治疗后，10例患者中有5例上呼吸道感染（URIs）和发热性疾病的发作频率降低。6例患者中有5例不再频繁发生肠炎。2例先前频繁感染的患者在接受DF治疗后未出现肺炎和中耳炎。3个月内患者肤色有所改善。大多数患者在相同血细胞比容水平下变得更加活跃。8例患者的身高和体重正常。所有患者的输血总量显著减少。对于无力使用输液泵和完整铁螯合治疗方案的患者，建议每周由RBIT给予DF输注。
Zotero 插件