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患者门户进行药物重整对药物差异的影响:一项随机非劣效性研究。

The Effect of Medication Reconciliation via a Patient Portal on Medication Discrepancies: A Randomized Noninferiority Study.

机构信息

Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands; Department of Hospital Pharmacy, St Jansdal Hospital, Harderwijk, the Netherlands; Department of Hospital Pharmacy, Erasmus MC, Erasmus University Medical Center, Rotterdam, the Netherlands.

Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands.

出版信息

J Am Med Dir Assoc. 2021 Dec;22(12):2553-2558.e1. doi: 10.1016/j.jamda.2021.03.022. Epub 2021 Apr 24.

Abstract

BACKGROUND

Medication reconciliation has become standard care to prevent medication transfer errors. However, this process is time-consuming but could be more efficient when patients are engaged in medication reconciliation via a patient portal.

OBJECTIVES

To explore whether medication reconciliation by the patient via a patient portal is noninferior to medication reconciliation by a pharmacy technician.

DESIGN (INCLUDING INTERVENTION): Open randomized controlled noninferiority trial. Patients were randomized between medication reconciliation via a patient portal (intervention) or medication reconciliation by a pharmacy technician at the preoperative screening (usual care).

SETTING AND PARTICIPANTS

Patients scheduled for elective surgery using at least 1 chronic medication were included.

MEASURES

The primary endpoint was the number of medication discrepancies compared to the electronic nationwide medication record system (NMRS). For the secondary endpoint, time investment of the pharmacy technician for the medication reconciliation interview and patient satisfaction were studied. Noninferiority was analyzed with an independent t test, and the margin was set at 20%.

RESULTS

A total of 499 patients were included. The patient portal group contained 241 patients; the usual care group contained 258 patients. The number of medication discrepancies was 2.6 ± 2.5 in the patient portal group and 2.8 ± 2.7 in the usual care group. This was not statistically different and within the predefined noninferiority margin. Patients were satisfied with the use of the patient portal tool. Also, the use of the portal can save on average 6.8 minutes per patient compared with usual care.

CONCLUSIONS AND IMPLICATIONS

Medication reconciliation using a patient portal is noninferior to medication reconciliation by a pharmacy technician with respect to medication discrepancies, and saves time in the medication reconciliation process. Future studies should focus on identifying patient characteristics for successful implementation of patient portal medication reconciliation.

摘要

背景

用药核对已成为防止用药转接错误的标准护理措施。然而,当患者通过患者门户参与用药核对时,该过程可以更高效,但耗时。

目的

探索患者通过患者门户进行用药核对是否不劣于药剂师进行用药核对。

设计(包括干预措施):开放性随机对照非劣效性试验。患者被随机分配至通过患者门户进行用药核对(干预组)或在术前筛查时由药剂师进行用药核对(常规护理组)。

地点和参与者

纳入计划接受择期手术且至少使用 1 种慢性病药物的患者。

测量指标

主要终点是与电子全国用药记录系统(NMRS)相比,用药差异的数量。次要终点是研究药剂师进行用药核对访谈的时间投入和患者满意度。采用独立 t 检验进行非劣效性分析,边界设定为 20%。

结果

共纳入 499 例患者。患者门户组 241 例,常规护理组 258 例。患者门户组的用药差异数量为 2.6±2.5,常规护理组为 2.8±2.7。这两组之间无统计学差异,且在预设的非劣效性边界内。患者对使用患者门户工具感到满意。与常规护理相比,使用门户平均可为每位患者节省 6.8 分钟的时间。

结论和意义

与药剂师进行用药核对相比,使用患者门户进行用药核对在用药差异方面不劣效,并且可以节省用药核对过程中的时间。未来的研究应重点确定成功实施患者门户用药核对的患者特征。

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