成人患者 CLOVES 综合征的诊断与治疗。
CLOVES Syndrome Diagnosis and Treatment in an Adult Patient.
机构信息
Life and Health Science Research Institute (ICVS), School of Health Science, University of Minho; Serviço de Cirurgia Vascular e Centro Académico do Hospital da Senhora da Oliveira Guimarães, Portugal.
Vascular Anomalies Center, Department of Pediatric Surgery, La Paz Children's Hospital, Madrid, Spain.
出版信息
Ann Vasc Surg. 2021 Aug;75:533.e5-533.e9. doi: 10.1016/j.avsg.2021.03.044. Epub 2021 Apr 24.
CLOVES syndrome is a rare, nonheritable sporadic overgrowth disorder. In the world 130-200 cases have been reported. This is the first case of CLOVES described in Portugal, which had been not been diagnosed for the last 36 years. With this paper, the authors look to highlight the clinical features of this syndrome so that it does not go unrecognized in daily practice. The authors also underline the efficacy and safety of sirolimus, and that this treatment should not be denied, even in adult patients.
CLOVES 综合征是一种罕见的、非遗传性的散发性过度生长疾病。在世界范围内，已经报告了 130-200 例病例。这是葡萄牙首例描述的 CLOVES 病例，该病例在过去 36 年中一直未被诊断出来。通过本文，作者旨在强调该综合征的临床特征，以免在日常实践中漏诊。作者还强调了西罗莫司的疗效和安全性，即使是在成年患者中，也不应拒绝这种治疗。
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