William R. Pritchard Veterinary Medical Teaching Hospital, University of California - Davis, One Garrod Drive, Davis, CA 95616, USA.
William R. Pritchard Veterinary Medical Teaching Hospital, University of California - Davis, One Garrod Drive, Davis, CA 95616, USA.
J Vet Cardiol. 2021 Jun;35:101-107. doi: 10.1016/j.jvc.2021.03.007. Epub 2021 Mar 29.
A cat previously diagnosed with valvular aortic stenosis developed acute respiratory distress. A new continuous heart murmur was noted on physical exam. Echocardiographic examination revealed vegetative lesions on the aortic valve and continuously shunting blood flow from the aorta into the left atrium. Despite initial treatment for left-sided congestive heart failure, the cat died suddenly. In addition to confirming aortic valve endocarditis and an acquired aorto-left atrial shunt, pathological examination identified vegetative lesions on the luminal surface of the ascending aorta. Although antemortem aerobic blood culture, 16s bacterial ribosomal DNA PCR, and Bartonella PCR failed to identify causative organisms, Escherichia coli was identified on postmortem tissue culture of the aortic lesion. This represented a unique case of primary valvular aortic stenosis with secondary infective aortic endocarditis, infective aortic endarteritis, and aorto-left atrial fistula in a cat. It highlighted potential adverse outcomes of aortic stenosis that are more commonly recognized in humans and dogs.
一只先前被诊断为主动脉瓣狭窄的猫出现急性呼吸窘迫。体格检查时发现新的连续性心杂音。超声心动图检查显示主动脉瓣有赘生物病变，并持续将血流从主动脉分流到左心房。尽管最初针对左侧充血性心力衰竭进行了治疗，但这只猫还是突然死亡。除了确认主动脉瓣心内膜炎和获得性的主动脉-左心房分流外，病理检查还发现升主动脉腔面有赘生物病变。尽管生前需氧血培养、16s 细菌核糖体 DNA PCR 和巴尔通体 PCR 未能鉴定出病原体，但在主动脉病变的尸检组织培养中鉴定出大肠杆菌。这是一例在猫中罕见的原发性主动脉瓣狭窄伴继发性感染性主动脉心内膜炎、感染性主动脉动脉炎和主动脉-左心房瘘的独特病例。它强调了主动脉瓣狭窄在猫中更常见的潜在不良后果，这些后果在人类和狗中更为人所知。
