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交界性神经管形成：原发性和继发性神经管之间的连接

Junctional Neurulation : A Junction between Primary and Secondary Neural Tubes.

作者信息

Kim Kyung Hyun, Lee Ji Yeoun

机构信息

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, Korea.

Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Korea.

出版信息

J Korean Neurosurg Soc. 2021 May;64(3):374-379. doi: 10.3340/jkns.2021.0021. Epub 2021 Apr 29.

DOI:10.3340/jkns.2021.0021
PMID:33906341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8128517/
Abstract

Recent case reports of junctional neural tube defect (JNTD) which is a peculiar type of spinal anomaly showing the functional disconnection of the primary and secondary neural tubes has risen interest in the process of junctional neurulation (the connection between the two neural tubes) during development. This article summarizes the clinical features of the JNTD and reviews the literature on the basic research on junctional neurulation.

摘要

最近有关交界性神经管缺陷（JNTD）的病例报告引发了人们对发育过程中交界性神经胚形成（两个神经管之间的连接）过程的兴趣，JNTD是一种特殊类型的脊柱异常，表现为原发性和继发性神经管的功能分离。本文总结了JNTD的临床特征，并回顾了有关交界性神经胚形成基础研究的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6be8/8128517/33cbec8fa1ba/jkns-2021-0021f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6be8/8128517/33cbec8fa1ba/jkns-2021-0021f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6be8/8128517/33cbec8fa1ba/jkns-2021-0021f1.jpg

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本文引用的文献

1
Reply to the comments by Eibach et al.对艾巴赫等人评论的回复
Childs Nerv Syst. 2020 Jun;36(6):1097. doi: 10.1007/s00381-020-04592-9. Epub 2020 Apr 8.
2
Do junctional neural tube defect and segmental spinal dysgenesis have the same pathoembryological background?交界性神经管缺陷和节段性脊柱发育不良是否具有相同的病理胚胎学背景？
Childs Nerv Syst. 2020 Feb;36(2):241-250. doi: 10.1007/s00381-019-04425-4. Epub 2019 Dec 10.
3
Junctional neural tube defect: a supporting case report.交界性神经管缺陷：一例支持性病例报告。
构建咽胚期：将头部的初级轴组织与尾部的后部轴组织连接起来。
Cells Dev. 2023 Dec;176:203866. doi: 10.1016/j.cdev.2023.203866. Epub 2023 Jun 30.
Childs Nerv Syst. 2018 Aug;34(8):1447-1448. doi: 10.1007/s00381-018-3855-1. Epub 2018 Jun 3.
4
A case of junctional neural tube defect associated with a lipoma of the filum terminale: a new subtype of junctional neural tube defect?一例伴有终丝脂肪瘤的神经管交界性缺损：神经管交界性缺损的一种新亚型？
J Neurosurg Pediatr. 2018 Jun;21(6):601-605. doi: 10.3171/2018.1.PEDS17492. Epub 2018 Mar 30.
5
Surgical Treatment of Thoracolumbar Segmental Spinal Dysgenesis: Optimal Type of Fusion.胸腰段脊柱节段性发育异常的手术治疗：最佳融合类型
World Neurosurg. 2017 Oct;106:551-556. doi: 10.1016/j.wneu.2017.07.031. Epub 2017 Jul 14.
6
Segmental spinal dysgenesis associated with occult dysraphism: Considerations on management strategies.与隐性脊柱裂相关的节段性脊柱发育不全：管理策略的思考
J Craniovertebr Junction Spine. 2017 Apr-Jun;8(2):144-148. doi: 10.4103/jcvjs.JCVJS_35_17.
7
Junctional neural tube defect in a newborn: report of a fourth case.新生儿交界性神经管缺陷：第四例报告
Childs Nerv Syst. 2017 May;33(5):873-875. doi: 10.1007/s00381-017-3353-x. Epub 2017 Feb 28.
8
Unjoined primary and secondary neural tubes: junctional neural tube defect, a new form of spinal dysraphism caused by disturbance of junctional neurulation.原发性和继发性神经管未连接：交界性神经管缺陷，一种由交界性神经胚形成障碍引起的新型脊柱裂。
Childs Nerv Syst. 2017 Oct;33(10):1633-1647. doi: 10.1007/s00381-016-3288-7. Epub 2016 Oct 29.
9
Segmental spinal dysgenesis: a report of early surgical intervention and outcome in a 14-month-old child.节段性脊柱发育不良：一名14个月大儿童早期手术干预及结果报告。
Childs Nerv Syst. 2017 Feb;33(2):381-384. doi: 10.1007/s00381-016-3224-x. Epub 2016 Sep 9.
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