Kim Kyung Hyun, Lee Ji Yeoun
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, Korea.
Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Korea.
J Korean Neurosurg Soc. 2021 May;64(3):374-379. doi: 10.3340/jkns.2021.0021. Epub 2021 Apr 29.
Recent case reports of junctional neural tube defect (JNTD) which is a peculiar type of spinal anomaly showing the functional disconnection of the primary and secondary neural tubes has risen interest in the process of junctional neurulation (the connection between the two neural tubes) during development. This article summarizes the clinical features of the JNTD and reviews the literature on the basic research on junctional neurulation.
最近有关交界性神经管缺陷(JNTD)的病例报告引发了人们对发育过程中交界性神经胚形成(两个神经管之间的连接)过程的兴趣,JNTD是一种特殊类型的脊柱异常,表现为原发性和继发性神经管的功能分离。本文总结了JNTD的临床特征,并回顾了有关交界性神经胚形成基础研究的文献。