Yao Yu-Cheng, Kim Han Jo, Bannwarth Mathieu, Smith Justin, Bess Shay, Klineberg Eric, Ames Christopher P, Shaffrey Christopher I, Burton Douglas, Gupta Munish, Mundis Gregory M, Hostin Richard, Schwab Frank, Lafage Virginie
Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Spine Service, Hospital for Special Surgery, New York, NY, USA.
Global Spine J. 2023 May;13(4):932-939. doi: 10.1177/21925682211009178. Epub 2021 Apr 28.
Retrospective cohort study.
To compare the outcomes of patients with adult spinal deformity (ASD) following spinal fusion with the lowest instrumented vertebra (LIV) at L4/L5 versus S1/ilium.
A multicenter ASD database was evaluated. Patients were categorized into 2 groups based on LIV levels-groups L (fusion to L4/L5) and S (fusion to S1/ilium). Both groups were propensity matched by age and preoperative radiographic alignments. Patient demographics, operative details, radiographic parameters, revision rates, and health-related quality of life (HRQOL) scores were compared.
Overall, 349 patients had complete data, with a mean follow-up of 46 months. Patients in group S (n = 311) were older and had larger sagittal and coronal plane deformities than those in group L (n = 38). After matching, 28 patients were allocated to each group with similar demographic, radiographic, and clinical parameters. Sagittal alignment restoration at postoperative week 6 was significantly better in group S than in group L, but it was similar in both groups at the 2-year follow-up. Fusion to S1/ilium involved a longer operating time, higher PJK rates, and greater PJK angles than that to L4/L5. There were no significant differences in the complication and revision rates between the groups. Both groups showed significant improvements in HRQOL scores.
Fusion to S1/ilium had better sagittal alignment restoration at postoperative week 6 and involved higher PJK rates and greater PJK angles than that to L4/L5. The clinical outcomes and rates of revision surgery and complications were similar between the groups.
回顾性队列研究。
比较成人脊柱畸形(ASD)患者在L4/L5处与S1/髂骨处融合至最低固定椎体(LIV)后的手术效果。
评估一个多中心ASD数据库。根据LIV水平将患者分为两组——L组(融合至L4/L5)和S组(融合至S1/髂骨)。两组在年龄和术前影像学对线方面进行倾向匹配。比较患者人口统计学、手术细节、影像学参数、翻修率以及健康相关生活质量(HRQOL)评分。
总体而言,349例患者有完整数据,平均随访46个月。S组(n = 311)患者比L组(n = 38)患者年龄更大,矢状面和冠状面畸形更大。匹配后,每组分配28例患者,其人口统计学、影像学和临床参数相似。术后第6周时,S组矢状面矫正明显优于L组,但在2年随访时两组相似。融合至S1/髂骨比融合至L4/L5手术时间更长,近端交界性后凸(PJK)发生率更高,PJK角度更大。两组之间的并发症和翻修率无显著差异。两组的HRQOL评分均有显著改善。
融合至S1/髂骨在术后第6周矢状面矫正更好,但比融合至L4/L5的PJK发生率更高、PJK角度更大。两组之间的临床结果、翻修手术率和并发症发生率相似。