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“混合性”嗜酸性细胞瘤:集合管(贝利尼管)癌——这种极其罕见的肿瘤内共存所带来的风险

'Hybrid' oncocytoma: collecting duct (Bellini) carcinoma-the peril from this extremely rare intratumoural coexistence.

作者信息

Tsikopoulos Ioannis, Papadopoulos Dimitrios Ioannis, Charitopoulos Konstantinos, Gkekas Chrysovalantis

机构信息

Urology Department, 424 General Military Training Hospital, Thessaloniki, Greece.

Urology Department, Surgical Division, West Middlesex University Hospital, Isleworth, UK

出版信息

BMJ Case Rep. 2021 Apr 26;14(4):e241091. doi: 10.1136/bcr-2020-241091.

Abstract

We presented an extremely rare entity of 'hybrid' oncocytoma and collecting duct (Bellini) carcinoma. The intratumoural coexistence of benign and malignant cells may lead to false diagnosis and suboptimal treatment of an aggressive tumour. Diagnosis may be challenging if only based on imaging modalities. Even the established value of targeted renal biopsy may be questioned in such scarce cases. Consequently, active surveillance for small renal tumours shall not considered a widely safe management.

摘要

我们报告了一种极为罕见的“混合型”嗜酸细胞瘤和集合管(贝氏管)癌。肿瘤内良性和恶性细胞并存可能导致对侵袭性肿瘤的误诊和治疗不当。仅基于影像学检查手段进行诊断可能具有挑战性。在如此罕见的病例中,即使是靶向肾活检的既定价值也可能受到质疑。因此,对小肾肿瘤进行主动监测不应被视为一种广泛安全的管理方法。

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本文引用的文献

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Modern Pathologic Diagnosis of Renal Oncocytoma.肾嗜酸细胞瘤的现代病理诊断
J Kidney Cancer VHL. 2017 Oct 9;4(4):1-12. doi: 10.15586/jkcvhl.2017.96. eCollection 2017.
4
Characteristics and outcomes of tumors arising from the distal nephron.起源于远端肾单位的肿瘤的特征和结局。
Urology. 2012 Jul;80(1):140-6. doi: 10.1016/j.urology.2012.03.034. Epub 2012 May 23.

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