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小儿糖尿病酮症酸中毒致心肌损伤 1 例报告。

Myocardial injury in a pediatric patient with diabetic ketoacidosis: A case report.

机构信息

Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.

出版信息

Medicine (Baltimore). 2021 Apr 30;100(17):e25702. doi: 10.1097/MD.0000000000025702.

Abstract

RATIONALE

Diabetic ketoacidosis (DKA) can cause several complications. Among them, cardiac complications are the most fatal and difficult to detect. Cardiac markers are prognostic factors for morbidity and mortality in adult patients with DKA. But, there have been very few discussed cases in pediatrics. We report a case of severe DKA in child with elevated cardiac enzymes and prolonged QT interval.

PATIENT CONCERNS

A 12-year-old girl admitted by nausea, vomiting, and lethargy for 1 day.

DIAGNOSES

Her blood sugar level was initially undetectable by the capillary blood glucose meter, and blood gas analysis showed severe DKA with elevated cardiac enzymes and prolonged QT interval.

INTERVENTIONS

The patient was admitted to hospital and intensive intravenous fluid and regular insulin infusion were administered.

OUTCOMES

After 5 days of supportive care, the patient was fully recovered, discharged, and followed up in an outpatient clinic.

LESSONS

Since the relationship between DKA and myocardial injury has not been clearly elucidated, pediatricians and emergency physicians should remain careful throughout the recovery time as it can lead to life-threatening conditions in various courses.

摘要

背景

糖尿病酮症酸中毒(DKA)可引起多种并发症。其中,心脏并发症是最致命且难以发现的。心脏标志物是成人 DKA 患者发病率和死亡率的预后因素。但在儿科中讨论的病例很少。我们报告了一例儿童严重 DKA 伴有心肌酶升高和 QT 间期延长的病例。

病例描述

一名 12 岁女孩因恶心、呕吐和嗜睡 1 天入院。

诊断

毛细血管血糖仪最初无法检测到她的血糖水平,血气分析显示严重 DKA 伴有心肌酶升高和 QT 间期延长。

干预措施

患者住院并给予静脉补液和常规胰岛素输注。

结果

经过 5 天的支持治疗,患者完全康复,出院并在门诊随访。

教训

由于 DKA 与心肌损伤之间的关系尚未明确阐明,儿科医生和急诊医生应在整个恢复期间保持警惕,因为它可能导致各种病程中的危及生命的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/8084016/b1b60ee4af94/medi-100-e25702-g001.jpg

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